44508
海洛因 盐酸盐 溶液
~1 mg/mL in acetonitrile, analytical standard, for drug analysis
InChI key
FZJYQGFGNHGSFX-PVQKIFDLSA-N
InChI
1S/C21H23NO5.ClH/c1-11(23)25-16-6-4-13-10-15-14-5-7-17(26-12(2)24)20-21(14,8-9-22(15)3)18(13)19(16)27-20;/h4-7,14-15,17,20H,8-10H2,1-3H3;1H/t14-,15+,17-,20-,21-;/m0./s1
SMILES string
Cl.CN1CC[C@]23[C@H]4Oc5c(OC(C)=O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4OC(C)=O)c35
assay
≥98.5% (HPLC)
shelf life
limited shelf life, expiry date on the label
drug control
USDEA Schedule I; Home Office Schedule 1; regulated under CDSA - not available from Sigma-Aldrich Canada
concentration
~1 mg/mL in acetonitrile
application(s)
pharmaceutical (small molecule)
storage temp.
2-8°C
Packaging
安瓿瓶，含 1.2mL 溶液
法规信息
新产品
此项目有
I Demaret et al.
Revue medicale de Liege, 68(5-6), 287-293 (2013-07-31)
Heroin (or diacetylmorphine), a depressant nervous central system, is a semi-synthetic opiate. Its main adverse effect, respiratory depression, can lead to death, especially after an intravenous injection. By loss of tolerance, an overdose can be lethal following heroin use after
D Adam Algren et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 9(1), 106-115 (2013-01-30)
During the summer of 2005, multiple cities in the United States began to report outbreaks of fentanyl-associated fatalities among illicit drug users. The objectives of this study were to (1) determine if an outbreak of fentanyl-associated fatalities occurred in mid-2005
Ruixue Yin et al.
International journal of medical sciences, 10(3), 299-306 (2013-02-21)
To investigate whether microvascular damage is involved in the pathogenesis of heroin induced spongiform leukoencephalopathy (HSLE). The brain tissues were collected from 4 HSLE patients and 5 controls and then fixed in 4% paraformaldehyde. The frontal lobe, corpus callosum and
Marc Walter et al.
Journal of clinical psychopharmacology, 33(2), 193-198 (2013-02-21)
Heroin dependence is associated with a stressful environment and with dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis. The present study examined the acute effects of intravenous heroin versus placebo on the HPA axis response in heroin-dependent patients. Twenty-eight heroin-dependent patients in
Hannah Skuse et al.
Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association, 20(9), 14-19 (2013-03-23)
This article discusses the administration of intranasal diamorphine as an analgesia-in paediatric trauma care. The authors outline evidence for its use and discuss a recent multicentre safety study of an intranasal diamorphine product. In addition, they advise emergency department nurses
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