44783
Flupirtine
analytical standard
别名:
Ethyl-N-[2-amino-6-(4-fluorophenylmethylamino) pyridin-3-yl]carbamate
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关于此项目
经验公式（希尔记法）:
C15H17FN4O2
化学文摘社编号:
分子量:
304.32
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
260-503-8
Beilstein/REAXYS Number:
493526
MDL number:
InChI key
JUUFBMODXQKSTD-UHFFFAOYSA-N
InChI
1S/C15H17FN4O2/c1-2-22-15(21)19-12-7-8-13(20-14(12)17)18-9-10-3-5-11(16)6-4-10/h3-8H,2,9H2,1H3,(H,19,21)(H3,17,18,20)
SMILES string
FC1=CC=C(CNC2=NC(N)=C(NC(OCC)=O)C=C2)C=C1
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
veterinary
format
neat
storage temp.
2-8°C
Quality Level
General description
Flupirtine belongs to N-methyl-D-aspartate class of drugs. It is a centrally acting non opioid analgesic with muscle relaxant and neuroprotective properties.
Application
Flupirtine may be used as a reference drug for the determination of flupirtine in biological samples by liquid chromatography combined with tandem mass spectrometry (HPLC-MS/MS).
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_c
Not applicable
Bioanalytical method validation and quantification of flupirtine in canine plasma by HPLC with spectrofluorimetric detection.
De Vito V, et al.
American Journal of Animal and Veterinary Sciences, 10(2), 91-100 (2015)
Flupirtine Determination in Human Blood Plasma by HPLC with Mass-Spectrometric Detection and its Application to Pharmacokinetic Studies.
Krasnykh L M, et al.
Pharma Chemica, 51(12), 1123-1128 (2018)
Antioxidant properties of the triaminopyridine, flupirtine. Biochemical pharmacology
Gassen M, et al.
Biochemical Pharmacology, 56(10), 1323-1329 (1998)
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