46111
2-甲氧基-5-甲基苯胺
analytical standard
别名:
5-甲基-邻茴香胺, 6-甲氧基-间甲苯胺, 对甲酚定
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关于此项目
线性分子式:
CH3OC6H3(CH3)NH2
化学文摘社编号:
分子量:
137.18
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
204-419-1
Beilstein/REAXYS Number:
637071
MDL number:
InChI key
WXWCDTXEKCVRRO-UHFFFAOYSA-N
InChI
1S/C8H11NO/c1-6-3-4-8(10-2)7(9)5-6/h3-5H,9H2,1-2H3
SMILES string
COc1ccc(C)cc1N
grade
analytical standard
vapor density
4.7 (vs air)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
bp
235 °C (lit.)
Quality Level
application(s)
cleaning products
cosmetics
environmental
food and beverages
personal care
format
neat
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General description
2-Methoxy-5-methylaniline is grouped under the class of aromatic amines (AAs), which are extensively utilized as intermediates in the synthesis of rubbers, plastics, dyes, etc. AAs are deemed as environmental pollutants as well as human carcinogens.
This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)
Application
2-Methoxy-5-methylaniline may be used as an analytical standard for the determination of the analyte in wastewater, textiles, and commercial hair dye samples by various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
230.0 °F - closed cup
flash_point_c
110 °C - closed cup
ppe
Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
Rama Jeevan Ganesh Jeevan et al.
Electrophoresis, 23(4), 584-590 (2002-03-01)
Analysis of carcinogenic substances is a high-priority area. Carcinogenic arylamines draw the analyst's attention because dyes and pigments are in production and used in large volumes. Identification of carcinogenic isomers of arylamines employing micellar electrokinetic chromatography (MEKC), a mode of
P Sutthivaiyakit et al.
Analytical and bioanalytical chemistry, 381(1), 268-276 (2005-02-08)
A confirmation method for the determination of 18 aromatic amines originating from azo dyes after reductive cleavage was developed. The method is based on the use of high-performance liquid chromatography/tandem mass spectrometry with atmospheric-pressure chemical ionization. For the identification of
Determination of some banned aromatic amines in waste water using micellar liquid chromatography
Mourya SK, et al.
Analytical Methods : Advancing Methods and Applications, 3(9), 2032-2040 (2011)
G Reznik et al.
Anticancer research, 1(5), 279-286 (1981-01-01)
p-Cresidine was administered in the feed at either of two concentrations (0.5 and 1.0 percent) to groups of 50 male and 50 female F344 rats for 104 weeks. Fifty animals of each sex were placed on test as controls and
T L Horn et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45(1), 55-63 (2006-09-13)
A six-month study was conducted in p53(+/-) mice to evaluate the possible oncogenicity of resveratrol (3,5,4'-trihydroxy-trans-stilbene), a cancer chemopreventive agent present in grapes and other foods. p53(+/-) mice (25/sex/group) received daily gavage exposure to vehicle only (negative control), resveratrol doses
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