46149
21-乙酸肾上腺酮
VETRANAL®, analytical standard
别名:
皮质甾酮-21-乙酸酯, 皮质酮-21-乙酸酯
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关于此项目
经验公式（希尔记法）:
C23H32O5
化学文摘社编号:
分子量:
388.50
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
214-635-8
Beilstein/REAXYS Number:
3225312
MDL number:
Quality Level
InChI key
WKQCPUMQBMFPLC-ZWFCQKKLSA-N
InChI
1S/C23H32O5/c1-13(24)28-12-20(27)18-7-6-17-16-5-4-14-10-15(25)8-9-22(14,2)21(16)19(26)11-23(17,18)3/h10,16-19,21,26H,4-9,11-12H2,1-3H3/t16-,17-,18+,19-,21+,22-,23-/m0/s1
SMILES string
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@]4(C)[C@H](CC[C@@]24[H])C(=O)COC(C)=O
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
涉药品监管产品
此项目有
H Okahata et al.
Acta endocrinologica, 111(4), 539-545 (1986-04-01)
The effects of weaning (abrupt dietary changes from breast milk to solid food) and corticosterone injection on antral gastrin-like immunoreactivity (G-LI) concentrations and antral G-LI biosynthesis were studied in rats. A single dose of corticosterone acetate was injected in one
H Okahata et al.
Acta endocrinologica, 112(3), 383-387 (1986-07-01)
The effects of dietary changes from breast milk to solid food and corticosterone acetate administration on somatostatin-like immunoreactivity (SLI) in the gastric antrum and corpus were studied in young and adult rats. At 7 days of age, a single dose
M Qulali et al.
Alcoholism, clinical and experimental research, 16(3), 427-431 (1992-06-01)
Glucocorticoids induced ADH activity and mRNA 2- to 4-fold in rat hepatoma cells (H4IIE and H4IIEC3), but were reported not to alter ADH activity in rat liver. The failure of corticosteroids to induce ADH may have been due to the
D Filipini et al.
The Journal of steroid biochemistry and molecular biology, 39(2), 245-252 (1991-08-01)
The effects of various steroid hormones on the long-term potentiation (LTP) of the rat hippocampus were evaluated. LTP was elicited in the dentate gyrus of adrenalectomized animals with priming tetanic stimulation (200 Hz-0.03 cps) of its main afferent, the perforant
R Badrinarayanan et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 84(5), 745-754 (2006-12-15)
Clinical and experimental studies, including our own observations, have shown the adverse effects of excess glucocorticoids on testicular steroid hormone production. The present study was designed to gain insight into the molecular mechanisms by which excess corticosterone impairs Leydig cell
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