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Merck
CN

46160

伊文思蓝

别名:

Direct Blue 53

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关于此项目

经验公式（希尔记法）:
C34H24N6Na4O14S4
化学文摘社编号:
314-13-6
分子量:
960.81
EC Number:
206-242-5
UNSPSC Code:
12171500
PubChem Substance ID:
24869872
Colour Index Number:
23860
MDL number:
MFCD00004021

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InChI key

ATNOAWAQFYGAOY-GPTZEZBUSA-J

InChI

1S/C34H28N6O14S4.4Na/c1-15-11-17(3-7-21(15)37-39-23-9-5-19-25(55(43,44)45)13-27(57(49,50)51)31(35)29(19)33(23)41)18-4-8-22(16(2)12-18)38-40-24-10-6-20-26(56(46,47)48)14-28(58(52,53)54)32(36)30(20)34(24)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4/b39-37+,40-38+;;;;

SMILES string

[Na+].[Na+].[Na+].[Na+].Cc1cc(ccc1\N=N\c2ccc3c(cc(c(N)c3c2O)S([O-])(=O)=O)S([O-])(=O)=O)-c4ccc(\N=N\c5ccc6c(cc(c(N)c6c5O)S([O-])(=O)=O)S([O-])(=O)=O)c(C)c4

suitability

suitable for microscopy

Gene Information

human ... PTPN1(5770), PTPRF(5792)

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H350

Hazard Classifications

Carc. 1B

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Zequan Yang et al.
American journal of respiratory cell and molecular biology, 40(3), 375-381 (2008-09-13)
Reactive oxygen species (ROS) play a crucial role in ischemia-reperfusion (IR) injury after lung transplantation. We hypothesized that NADPH oxidase derived from bone marrow (BM) cells contributes importantly to lung IR injury. An in vivo mouse model of lung IR
Svitlana Garbuzova-Davis et al.
PloS one, 6(3), e16601-e16601 (2011-03-17)
Sanfilippo syndrome type B (MPS III B) is caused by a deficiency of α-N-acetylglucosaminidase enzyme, leading to accumulation of heparan sulfate within lysosomes and eventual progressive cerebral and systemic multiple organ abnormalities. However, little is known about the competence of
Fengshan Yu et al.
Journal of neurotrauma, 25(3), 184-195 (2008-03-21)
Matrix metalloproteinase-9 (MMP-9) activation plays an important role in blood-brain barrier (BBB) dysfunction after central nervous system injury. Oxidative stress is also implicated in the pathogenesis after cerebral ischemia and spinal cord injury (SCI), but the relationship between MMP-9 activation
Edward Htun van der Horst et al.
Neoplasia (New York, N.Y.), 10(4), 340-347 (2008-04-09)
Midkine (MDK) is a heparin-binding growth factor involved in growth, survival, migration, and differentiation of various target cells and dysregulation of MDK signaling is implicated in a variety of inflammatory diseases and cancers. Although MDK has been reported to act
A Zarbock et al.
British journal of pharmacology, 155(3), 357-364 (2008-07-01)
Acute lung injury (ALI) remains a major challenge in critical care medicine. Both neutrophils and chemokines have been proposed as key components in the development of ALI. The main chemokine receptor on neutrophils is CXCR2, which regulates neutrophil recruitment and
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