46297
呋喃唑酮
VETRANAL®, analytical standard
别名:
3-(5-硝基呋喃甲叉氨基)-2-噁唑烷酮
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关于此项目
经验公式（希尔记法）:
C8H7N3O5
化学文摘社编号:
分子量:
225.16
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-653-3
Beilstein/REAXYS Number:
8317414
MDL number:
InChI key
PLHJDBGFXBMTGZ-WEVVVXLNSA-N
InChI
1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+
SMILES string
[O-][N+](=O)c1ccc(\C=N\N2CCOC2=O)o1
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
antibiotic activity spectrum
Gram-positive bacteria, parasites
application(s)
cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
format
neat
mode of action
enzyme | inhibits
Quality Level
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General description
Furazolidone is an effective antiprotozoal and antibacterial agent.
Application
Furazolidone may be used as a reference standard:
- For the determination of the analyte in pharmaceutical formulations by second-derivative spectrophotometry.
- For the determination of the analyte in animal feeds using liquid chromatography with ultraviolet and thermospray mass spectrometric detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Determination of furazolidone in animal feeds using liquid chromatography with UV and thermospray mass spectrometric detection.
McCracken RJ and Kennedy DG
Journal of Chromatography A, 771(1-2), 349- 354 (1997)
Formulation and advantages of furazolidone in liposomal drug delivery systems.
Alam MI, et al.
European Journal of Pharmaceutical Sciences, 84, 139- 145 (2016)
C V Prasad et al.
Journal of pharmaceutical and biomedical analysis, 21(5), 961-968 (2000-03-07)
A second-derivative spectrophotometric procedure has been developed for the simultaneous determination of tinidazole (TD), furazolidone (FD) and diloxanide furoate (DF) in a commercial preparation. The method consists of the utilization of second-derivative absorption spectra of tablet extract in distilled water
B H Ali
Veterinary research communications, 6(1), 1-11 (1983-01-01)
The pharmacological and toxicological properties of furazolidone have been briefly reviewed. Among the most important pharmacological actions of furazolidone is the inhibition of mono- and diamine oxidase activities, which seem to depend, at least in some species, on the presence
In vivo and in vitro metabolic studies of furazolidone: a risk evaluation.
L H Vroomen et al.
Drug metabolism reviews, 22(6-8), 663-676 (1990-01-01)
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