47580
5-氟脲嘧啶
≥99.0% (HPLC)
别名:
5-氟尿嘧啶 1β-D-呋喃核苷, 皮毛
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关于此项目
经验公式（希尔记法）:
C9H11FN2O6
化学文摘社编号:
分子量:
262.19
EC Number:
206-260-3
UNSPSC Code:
41106305
PubChem Substance ID:
Beilstein/REAXYS Number:
33662
MDL number:
InChI key
FHIDNBAQOFJWCA-UAKXSSHOSA-N
InChI
1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=C(F)C(=O)NC2=O
biological source
synthetic
assay
≥99.0% (HPLC)
optical activity
[α]20/D +18±1°, c = 1% in H2O
mp
182-184 °C
storage temp.
2-8°C
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
法规信息
新产品
此项目有
Mingjie Chen et al.
The Plant cell, 23(8), 2991-3006 (2011-08-11)
Nucleotides are synthesized from de novo and salvage pathways. To characterize the uridine salvage pathway, two genes, UKL1 and UKL2, that tentatively encode uridine kinase (UK) and uracil phosphoribosyltransferase (UPRT) bifunctional enzymes were studied in Arabidopsis thaliana. T-DNA insertions in
I Casafont et al.
Neuroscience, 140(2), 453-462 (2006-03-28)
In this study we have used the transcription assay with 5'-fluorouridine incorporation into nascent RNA to analyze the nuclear organization and dynamics of transcription sites in rat trigeminal ganglia neurons. The 5'-FU administrated by i.p. injection was successfully incorporated into
Rita Humeniuk et al.
Molecular cancer therapeutics, 8(5), 1037-1044 (2009-04-23)
5-Fluorouracil (5-FU) continues to be widely used for treatment of gastrointestinal cancers. Because many tumors show primary or acquired resistance, it is important to understand the molecular basis underlying the mechanism of resistance to 5-FU. In addition to its effect
Olaf H Temmink et al.
The international journal of biochemistry & cell biology, 39(3), 565-575 (2006-11-14)
Thymidine phosphorylase (TP) and uridine phosphorylase (UP) are often upregulated in solid tumors and catalyze the phosphorolysis of natural (deoxy)nucleosides and a wide variety of fluorinated pyrimidine nucleosides. Because the relative contribution of each of the two enzymes to these
Alvaro A A de Queiroz et al.
Acta biomaterialia, 2(6), 641-650 (2006-08-01)
The effect of gamma-radiation doses of 12.5-380 kGy on the infrared spectra, gel content, mechanical properties, and the release of oxobutyl-5-fluoro-2'-deoxyuridine (OfdUrd, an antitumor agent) from poly(ethylene-co-vinyl acetate) (EVA) films was studied. The results showed that the application of radiation
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