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Merck
CN

484407

1-甲氧基-2-丙醇

greener alternative

≥99.5%

别名:

DOWANOL® PM, 丙二醇单甲醚, 丙二醇甲醚

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线性分子式:
CH3CH(OH)CH2OCH3
化学文摘社编号:
分子量:
90.12
UNSPSC Code:
12352100
NACRES:
NA.21
PubChem Substance ID:
EC Number:
203-539-1
Beilstein/REAXYS Number:
1731270
MDL number:
Assay:
≥99.5%
Application(s):
microbiology
Bp:
118-119 °C (lit.)
Vapor pressure:
10.9 mmHg ( 25 °C)
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产品名称

1-甲氧基-2-丙醇, ≥99.5%

InChI key

ARXJGSRGQADJSQ-UHFFFAOYSA-N

InChI

1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3

SMILES string

CC(O)COC

vapor density

3.12 (vs air)

vapor pressure

10.9 mmHg ( 25 °C)

product line

ReagentPlus®

assay

≥99.5%

form

liquid

autoignition temp.

532 °F

expl. lim.

13.8 %

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

≤0.001% water

refractive index

n20/D 1.403 (lit.)

bp

118-119 °C (lit.)

mp

-97 °C

solubility

water: miscible

density

0.916 g/mL at 25 °C (lit.)

application(s)

microbiology

greener alternative category

Quality Level

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General description

1-甲氧基-2-丙醇(丙二醇甲醚,PGME),是一种甘醇醚,可通过在ZnMgAl(锌-镁-铝)催化剂存在下由环氧丙烷与甲醇反应进行合成。它在不同土壤类型中的微生物降解已被研究。通过对F344大鼠和B6C3F1小鼠的吸入研究,已得到PGME的口服参考剂量(RfD)和吸入参考浓度(RfC)值。
我们致力于为您提供更环保的替代产品,以符合“绿色化学的 12 项原则”的一项或多项原则要求。单醚,特别是丙二醇甲醚(PGME)作为一种无污染溶剂已广泛应用于制药、化工和化装品行业的精细有机合成应用中,符合“更安全的溶剂和辅助剂”的要求。 点击此处了解更多信息。

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark

signalword

Warning

hcodes

Hazard Classifications

Flam. Liq. 3 - STOT SE 3

target_organs

Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

88.7 °F - closed cup - (External MSDS)

flash_point_c

31.5 °C - closed cup - (External MSDS)

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Influence of acid-base properties of ZnMgAl-mixed oxides for the synthesis of 1-methoxy-2-propanol.
Cheng W, et al.
Applied Clay Science, 42(1), 111-115 (2008)
Biodegradation of glycol ethers in soil.
Gonsior SJ and West RJ.
Environmental Toxicology and Chemistry / Setac, 14(8), 1273-1279 (1995)
Rei Momose et al.
Organic letters, 15(8), 2010-2013 (2013-04-11)
Three new alkaloids, hyrtimomines A-C (1-3), were isolated from an Okinawan marine sponge Hyrtios sp. The structures of 1-3 were elucidated on the basis of spectroscopic analysis and application of a phenylglycine methyl ester (PGME) method. Hyrtimomines A (1) and
H H Emmen et al.
Toxicology letters, 140-141, 249-259 (2003-04-05)
The objective of this study was to establish the possible occurrence of eye irritation and subjective symptoms in human volunteers exposed to propylene glycol monomethyl ether (PGME) vapour at concentrations of 0, 100 and 150 ppm. Testing was conducted in
Lumír O Hanus et al.
Phytochemistry, 63(8), 869-875 (2003-08-05)
A new trinorsesterterpene glycoside was isolated from the ethanol extract of the American fern Woodwardia virginica having a 3-[6-(4,8-dimethyl-nona-1,3,7-trienyl)-4-hydroxy-2,6-dimethyl-cyclohex-1-enyl]-3-hydroxypropionic acid, as the aglycone and a saccharide moiety linked at C-4 to glucoses, xylose or arabinofuranose. The structure was elucidated using

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