484407
1-甲氧基-2-丙醇
≥99.5%
别名:
DOWANOL® PM, 丙二醇单甲醚, 丙二醇甲醚
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关于此项目
线性分子式:
CH3CH(OH)CH2OCH3
化学文摘社编号:
分子量:
90.12
Beilstein:
1731270
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.21
蒸汽密度
3.12 (vs air)
质量水平
蒸汽压
10.9 mmHg ( 25 °C)
产品线
ReagentPlus®
方案
≥99.5%
表单
liquid
自燃温度
532 °F
expl. lim.
13.8 %
环保替代产品特性
Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.
sustainability
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杂质
≤0.001% water
折射率
n20/D 1.403 (lit.)
沸点
118-119 °C (lit.)
mp
-97 °C
溶解性
water: miscible
密度
0.916 g/mL at 25 °C (lit.)
应用
microbiology
环保替代产品分类
, Aligned
SMILES字符串
CC(O)COC
InChI
1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3
InChI key
ARXJGSRGQADJSQ-UHFFFAOYSA-N
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一般描述
1-甲氧基-2-丙醇(丙二醇甲醚，PGME)，是一种甘醇醚，可通过在ZnMgAl（锌-镁-铝）催化剂存在下由环氧丙烷与甲醇反应进行合成。它在不同土壤类型中的微生物降解已被研究。通过对F344大鼠和B6C3F1小鼠的吸入研究，已得到PGME的口服参考剂量（RfD）和吸入参考浓度（RfC）值。
我们致力于为您提供更环保的替代产品，以符合“绿色化学的 12 项原则”的一项或多项原则要求。单醚，特别是丙二醇甲醚（PGME）作为一种无污染溶剂已广泛应用于制药、化工和化装品行业的精细有机合成应用中，符合“更安全的溶剂和辅助剂”的要求。 点击此处了解更多信息。
法律信息
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险声明
危险分类
Flam. Liq. 3 - STOT SE 3
靶器官
Central nervous system
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
88.7 °F - closed cup - (External MSDS)
闪点(°C)
31.5 °C - closed cup - (External MSDS)
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
Influence of acid-base properties of ZnMgAl-mixed oxides for the synthesis of 1-methoxy-2-propanol.
Cheng W, et al.
Applied Clay Science, 42(1), 111-115 (2008)
Biodegradation of glycol ethers in soil.
Gonsior SJ and West RJ.
Environmental Toxicology and Chemistry / Setac, 14(8), 1273-1279 (1995)
Rei Momose et al.
Organic letters, 15(8), 2010-2013 (2013-04-11)
Three new alkaloids, hyrtimomines A-C (1-3), were isolated from an Okinawan marine sponge Hyrtios sp. The structures of 1-3 were elucidated on the basis of spectroscopic analysis and application of a phenylglycine methyl ester (PGME) method. Hyrtimomines A (1) and
R A Corley et al.
Toxicology letters, 156(1), 193-213 (2005-02-12)
Propylene glycol monomethyl ether (PM), along with its acetate, is the most widely used of the propylene glycol ether family of solvents. The most common toxic effects of PM observed in animal studies include sedation, very slight alpha(2u)-globulin mediated nephropathy
Nancy B Hopf et al.
Toxicology letters, 211(1), 77-84 (2012-03-17)
Aging adults represent the fastest growing population segment in many countries. Physiological and metabolic changes in the aging process may alter how aging adults biologically respond to pollutants. In a controlled human toxicokinetic study (exposure chamber; 12 m³), aging volunteers
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