assay
≥99.0% (sum of enantiomers, GC)
optical activity
[α]20/D +100±2°, c = 5% in chloroform
mp
111-113 °C
solubility
chloroform: 0.1 g/mL, clear, colorless
application(s)
microbiology
SMILES string
CC(=O)OC[C@H]1O[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O
Other Notes
选择性 1-O-脱乙酰反应
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1A
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
J. Fiandor et al.
Synthesis, 1121-1121 (1985)
Preparation of nucleoside-carbohydrate phosphodiester prodrug analogues by chemoenzymatic procedure.
Tatiana Rodríguez-Pérez et al.
Nucleic acids symposium series (2004), (52)(52), 101-102 (2008-09-09)
An efficient synthesis protocol for the glucosyl-nucleoside phosphodiester derivatives has been developed. These mononucleotides were designed to act as pronucleotides with potential to deliver the parent compound as its monophosphate. Key step of the synthesis is the regioselective hydrolysis of
W J Malaisse
International journal of molecular medicine, 2(4), 383-388 (1998-12-19)
The two anomers of L-glucose pentaacetate were recently found to stimulate insulin release. The insulinotropic action of these esters cannot be attributed to the catabolism in islet cells of their glucidic or acetic moieties. The present review deals with an
Monosaccharide esters: clinically relevant?
E O Balasse
Acta clinica Belgica, 57(2), 47-48 (2002-08-03)
E Olivares et al.
Cell biochemistry and function, 16(4), 233-237 (1998-12-19)
The esterification of several monosaccharides, such as D-glucose, D-mannoheptulose and 2-deoxy-D-glucose was recently reported to increase their biological efficiency as either nutrient or antimetabolic agent. In the present study, however, the tetraacetate ester of streptozotocin was unexpectedly found to be
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