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Merck
CN

51020

鸟嘌呤

puriss., ≥99.0% (HPLC)

别名:

2-乌嘌呤, 2-氨基-1,7-二氢-6H-嘌呤-6-酮, 2-氨基-6-羟基嘌呤

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关于此项目

经验公式(希尔记法):
C5H5N5O
化学文摘社编号:
分子量:
151.13
EC Number:
200-799-8
UNSPSC Code:
12352005
MDL number:
Beilstein/REAXYS Number:
9680
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grade

puriss.

assay

≥99.0% (HPLC)

ign. residue

≤0.3%

mp

>300 °C (lit.)

SMILES string

NC1=Nc2[nH]cnc2C(=O)N1

InChI

1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)

InChI key

UYTPUPDQBNUYGX-UHFFFAOYSA-N

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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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分析证书(COA)

Lot/Batch Number

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In single-group studies, chromosomal rearrangements of the anaplastic lymphoma kinase gene (ALK) have been associated with marked clinical responses to crizotinib, an oral tyrosine kinase inhibitor targeting ALK. Whether crizotinib is superior to standard chemotherapy with respect to efficacy is
Zac Chatterton et al.
Clinical chemistry, 60(7), 995-1003 (2014-05-16)
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Wieneke A Buikhuisen et al.
The Lancet. Oncology, 14(6), 543-551 (2013-04-16)
Standard chemotherapy does not lead to long-term survival in patients with malignant pleural mesothelioma. Malignant pleural mesothelioma is strongly dependent on vasculature with high vessel counts and high concentrations of serum vascular growth factors. Thalidomide has shown antiangiogenic activity, and
Giovanni Maga et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(47), 18850-18855 (2013-11-06)
The bypass of DNA lesions by the replication fork requires a switch between the replicative DNA polymerase (Pol) and a more specialized translesion synthesis (TLS) Pol to overcome the obstacle. DNA Pol δ-interacting protein 2 (PolDIP2) has been found to

全球贸易项目编号

货号GTIN
186414-1G04061837613616
186414-5G04061838758156
186414-10X1G-N04061837613609
186414-5X5G-N04061837613623

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