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Merck
CN

52512

1,1,1,3,3,3-六氟-2-丙醇

puriss., ≥99.0% (GC)

别名:

HFP, 六氟异丙醇

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关于此项目

线性分子式:
(CF3)2CHOH
化学文摘社编号:
分子量:
168.04
EC Number:
213-059-4
UNSPSC Code:
12352104
PubChem Substance ID:
Beilstein/REAXYS Number:
1841007
MDL number:
Assay:
≥99.0% (GC)
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grade

puriss.

assay

≥99.0% (GC)

impurities

≤0.1% water

refractive index

n20/D 1.275 (lit.)

bp

59 °C (lit.)

mp

−4 °C (lit.)

density

1.596 g/mL at 25 °C (lit.)

SMILES string

OC(C(F)(F)F)C(F)(F)F

InChI

1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H

InChI key

BYEAHWXPCBROCE-UHFFFAOYSA-N

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Other Notes

用于肽和肽中间体的高溶性溶剂

pictograms

Health hazardCorrosion

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Repr. 2 - Skin Corr. 1A - STOT RE 2 Oral

target_organs

Central nervous system

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

No data available

flash_point_c

No data available

ppe

Faceshields, Gloves, Goggles

法规信息

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历史批次信息供参考:

分析证书(COA)

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L M Jungbauer et al.
Journal of molecular recognition : JMR, 22(5), 403-413 (2009-04-04)
Recent research has focused on soluble oligomeric assemblies of the 42 amino acid isoform of the amyloid-beta peptide (A beta 42) as the proximal cause of neuronal injury, synaptic loss, and the eventual dementia associated with Alzheimer's disease (AD). While
Thomas J Esparza et al.
Annals of neurology, 73(1), 104-119 (2012-12-12)
Although amyloid-beta (Aβ) peptide deposition into insoluble plaques is a pathological hallmark of Alzheimer disease; soluble oligomeric Aβ has been hypothesized to more directly underlie impaired learning and memory in dementia of the Alzheimer type. However, the lack of a
M. Narita et al.
Bulletin of the Chemical Society of Japan, 61, 281-281 (1988)
Margery L Evans et al.
Prion, 5(4), 323-334 (2011-12-14)
Amyloid formation is an ordered aggregation process, where β-sheet rich polymers are assembled from unstructured or partially folded monomers. We examined how two Escherichia coli cytosolic chaperones, DnaK and Hsp33, and a more recently characterized periplasmic chaperone, Spy, modulate the
Benjamin H Rotstein et al.
Chemical communications (Cambridge, England), 48(31), 3775-3777 (2012-03-21)
A novel class of reagents, thioester isocyanides, have been prepared and applied in the synthesis of peptide macrocycles. The isocyanide part of the molecule is deployed in a multicomponent macrocyclization step. This step is followed by chemoselective peptide ligation at

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