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Merck
CN

55040

2-甲基-8-喹啉醇

purum, ≥99.0% (NT)

别名:

8-羟基喹哪啶

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经验公式（希尔记法）:
C10H9NO
化学文摘社编号:
826-81-3
分子量:
159.18
EC Number:
212-562-6
UNSPSC Code:
12352100
PubChem Substance ID:
24879112
Beilstein/REAXYS Number:
119194
MDL number:
MFCD00006765

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grade

purum

assay

≥99.0% (NT)

bp

267 °C (lit.)

mp

71-73 °C

SMILES string

Cc1ccc2cccc(O)c2n1

InChI

1S/C10H9NO/c1-7-5-6-8-3-2-4-9(12)10(8)11-7/h2-6,12H,1H3

InChI key

NBYLBWHHTUWMER-UHFFFAOYSA-N

General description

2-Methyl-8-quinolinol is a methyl substituted quinolinol derivative that shows fungicidal property. It can also undergo complexation with transition metal complexes.

Application

2-Methyl-8-quinolinol (HqMe) may be used as a ligand for preparing bis (2-methyl-8-quinolinolato) aluminum(III)-μ-oxo-bis (2-methyl-8-quinolinolato ) aluminum (III). It may also be used in the preparation of a scandium 2-methyl-8-quinolinolate complex [Sc(qMe)4(H)].

pictograms

Environment
GHS09

signalword

Warning

hcodes

H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

282.2 °F - closed cup

flash_point_c

139 °C - closed cup

ppe

Eyeshields, Gloves

法规信息

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New type of arrangement of rare-earth quinolinolate. Molecular structure of scandium 2-methyl-8-quinolinolate.
Katkova MA, et al.
Inorgorganica Chimica Acta, 362(4), 1393-1395 (2009)
Infrared Spectra, Density Functional Theory and Hartree-Fock Theoretical Calculations of 2-Methyl-8-quinolinol.
Arici K and Yilmaz R.
Asian Journal of Chemistry, 25(13), 7106-7106 (2013)
Antifungal activity of 5-,7-, and 5,7-substituted 2-methyl-8-quinolinols.
Gershon H, et al.
Antimicrobial Agents and Chemotherapy, 1(5), 373-375 (1972)
The crystal and molecular structure of bis-(2-methyl-8-quinolinolato) oxovanadium (IV).
Shiro M and Fernando Q.
Journal of the Chemical Society. Chemical Communications, 1, 63-64 (1971)
Qi-Pin Qin et al.
European journal of medicinal chemistry, 92, 302-313 (2015-01-13)
[Pt(Q)2] (1) and [Pt(MQ)2] (2) exhibited enhanced cytotoxicity against BEL-7404, Hep-G2, NCI-H460, T-24, A549 tumor cells but low cytotoxicity on normal HL-7702 cells. 1 and 2 could cause the cell cycle arrest in G2 and S phase, respectively. While pifithrin-α

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