55591
羟甲唑啉 盐酸盐
analytical standard
别名:
2-（3-羟基-2,6-二甲基-4-叔丁基苄基）-2-咪唑啉 盐酸盐
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关于此项目
经验公式（希尔记法）:
C16H24N2O · HCl
化学文摘社编号:
分子量:
296.84
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
219-015-0
MDL number:
InChI key
BEEDODBODQVSIM-UHFFFAOYSA-N
InChI
1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H
SMILES string
Cl.Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C
grade
analytical standard
assay
≥99.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤0.5% water
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Quality Level
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)
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Application
Oxymetazoline hydrochloride may be used as a reference standard in the determination of oxymetazoline hydrochloride in nasal spray formulations using high performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
盐酸羟甲唑啉是一种部分 α2A-肾上腺素受体激动剂；5-HT1A、5-HT1B 和 5-HT1D 血清素受体的激动剂。它是 5-HT1C 血清素受体的混合激动剂-拮抗剂。
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Chronic 3 - Eye Dam. 1
存储类别
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
法规信息
监管及禁止进口产品
此项目有
Simultaneous determination of triamcinolone acetonide and oxymetazoline hydrochloride in nasal spray formulations by HPLC.
Sudsakorn S, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(5), 1273-1280 (2006)
Sylwia K Paszun et al.
Acta poloniae pharmaceutica, 70(6), 1079-1085 (2014-01-05)
The presented study aimed at the evaluation of hydrochlorothiazide influence on cilazapril stability in model mixture and fixed dose tablet formulation. The degradation of cilazapril in the presence of hydrochlorothiazide took place according to autocatalytic reaction kinetic mechanism, described mathematically
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