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Merck
CN

56011

2-羟基-5-硝基苄溴

~95% (AT)

别名:

α-溴-4-硝基邻甲酚, 2-溴甲基-4-硝基苯酚, Koshland I, Koshland 试剂 I

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关于此项目

线性分子式:
HOC6H3(NO2)CH2Br
化学文摘社编号:
分子量:
232.03
EC Number:
212-248-9
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1868798
MDL number:
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assay

~95% (AT)

mp

144-149 °C

storage temp.

2-8°C

SMILES string

Oc1ccc(cc1CBr)[N+]([O-])=O

InChI

1S/C7H6BrNO3/c8-4-5-3-6(9(11)12)1-2-7(5)10/h1-3,10H,4H2

InChI key

KFDPCYZHENQOBV-UHFFFAOYSA-N

Other Notes

在中性和酸性条件下用于色氨酸残基的修饰

法规信息

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A simplified procedure to determine tryptophan residues in proteins.
Y D Karkhanis et al.
Analytical biochemistry, 69(1), 55-60 (1975-11-01)
R L Lundblad et al.
Analytical biochemistry, 136(1), 93-100 (1984-01-01)
Previous studies on the isolation of peptides containing tryptophanyl residues modified with 2-hydroxy-5-nitrobenzyl bromide demonstrated multiple products of reaction at the same residue as well as technical difficulties in the primary structure analysis of peptides containing the modified tryptophanyl residue.
A HIGHLY REACTIVE COLORED REAGENT WITH SELECTIVITY FOR THE TRYPTOPHAN RESIDUE IN PROTEINS. 2-HYDROXY-5-NITROBENZYL BROMIDE.
H R HORTON et al.
Journal of the American Chemical Society, 87, 1126-1132 (1965-03-05)

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