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Merck
CN

56060

(±)-2-羟基辛酸

purum, ≥98.0% (T)

别名:

(±)-2-羟基辛酸

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关于此项目

线性分子式:
CH3(CH2)5CH(OH)COOH
化学文摘社编号:
分子量:
160.21
EC Number:
210-524-3
UNSPSC Code:
12352211
MDL number:
Beilstein/REAXYS Number:
1760638
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grade

purum

assay

≥98.0% (T)

mp

66-70 °C

storage temp.

2-8°C

SMILES string

CCCCCCC(O)C(O)=O

InChI

1S/C8H16O3/c1-2-3-4-5-6-7(9)8(10)11/h7,9H,2-6H2,1H3,(H,10,11)

InChI key

JKRDADVRIYVCCY-UHFFFAOYSA-N

Biochem/physiol Actions

(±)-2-羟基辛酸以己酸为底物抑制来自牛肝线粒体(Ki,500 uM)的纯化的中链acyl-CoA合成酶


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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M Duran et al.
European journal of pediatrics, 150(3), 190-195 (1991-01-01)
Two siblings were found to be affected by long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency, one of which died suddenly and unexpectedly on the 3rd day of life suffering from extreme hypoketotic hypoglycaemia. The younger sibling started to have feeding problems, lowered consciousness
J M Jones et al.
The Journal of biological chemistry, 275(17), 12590-12597 (2000-04-25)
Computer-based approaches identified three distinct human 2-hydroxy acid oxidase genes, HAOX1, HAOX2, and HAOX3, that encode proteins with significant sequence similarity to plant glycolate oxidase, a prototypical 2-hydroxy acid oxidase. The products of these genes are targeted to peroxisomes and
F Kasuya et al.
Biochemical pharmacology, 52(10), 1643-1646 (1996-11-22)
Molecular characteristics of carboxylic acids were investigated for the ability to inhibit a purified medium chain acyl-CoA synthetase, using hexanoic acid as a substrate. Salicylic acid, 4-methylsalicylic acid, 2-hydroxynaphtoic acid, and 2-hydroxyoctanoic acid, which do not act as substrates for