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Merck
CN

57280

3-吲哚乙腈

purum, ≥96.0% (GC)

别名:

3-(氰甲基)吲哚, IAN, NSC 523272, 吲哚-3-乙腈, 吲哚乙腈

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关于此项目

经验公式(希尔记法):
C10H8N2
化学文摘社编号:
分子量:
156.18
EC Number:
212-232-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
125488
MDL number:
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grade

purum

assay

≥96.0% (GC)

bp

157-160 °C/0.2 mmHg (lit.)

mp

33-36 °C

storage temp.

2-8°C

SMILES string

N#CCc1c[nH]c2ccccc12

InChI

1S/C10H8N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5H2

InChI key

DMCPFOBLJMLSNX-UHFFFAOYSA-N

Application

反应物用于制备:
  • 色氨酸双加氧酶抑制剂吡啶基-乙烯基-吲哚作为潜在的抗癌免疫调节剂
  • 组蛋白脱乙酰酶抑制剂
  • 潜在激酶抑制剂
  • Kv7/KCNQ 钾通道激活剂
  • 驱动蛋白特异性 MKLP-2 抑制剂
  • 杀虫剂
  • 潜在 PET 癌症显像剂
  • 作为动脉粥样硬化治疗的法尼酯 X 受体 (FXR) 激动剂
  • 丁酰胆碱酯酶抑制剂
  • 坏死性凋亡抑制剂

Other Notes

植物促生长剂。在烟草愈伤组织中促进愈伤组织生长与芽形成


存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

233.6 °F - closed cup

flash_point_c

112 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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S Oh et al.
Journal of applied microbiology, 113(3), 622-628 (2012-06-26)
Indole is a signalling molecule, produced by a number of Gram-positive and Gram-negative bacteria both in nature as well as clinical environments. Here, we explored the effect of bacterial indole and one of its main derivatives on the virulence of
Martin de Vos et al.
Plant physiology, 146(3), 916-926 (2008-01-15)
Like many crucifer-specialist herbivores, Pieris rapae uses the presence of glucosinolates as a signal for oviposition and larval feeding. Arabidopsis thaliana glucosinolate-related mutants provide a unique resource for studying the in vivo role of these compounds in affecting P. rapae
Nicole K Clay et al.
Science (New York, N.Y.), 323(5910), 95-101 (2008-12-20)
The perception of pathogen or microbe-associated molecular pattern molecules by plants triggers a basal defense response analogous to animal innate immunity and is defined partly by the deposition of the glucan polymer callose at the cell wall at the site