57670
碘乙酰胺
≥98.0% (AT), purum
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关于此项目
线性分子式:
ICH2CONH2
化学文摘社编号:
分子量:
184.96
UNSPSC Code:
12352202
PubChem Substance ID:
eCl@ss:
32035301
EC Number:
205-630-1
Beilstein/REAXYS Number:
1739080
MDL number:
InChI
1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
InChI key
PGLTVOMIXTUURA-UHFFFAOYSA-N
SMILES string
NC(=O)CI
grade
purum
assay
≥98.0% (AT)
storage temp.
2-8°C
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General description
May contain some chloracetamide.
Biochem/physiol Actions
碘乙酰胺在肽测序中胱氨酸残基的烷基化试剂。它是活性位点上含有胱氨酸的酶的的一种不可逆抑制剂。它与组氨酸残基的反应速度要慢得多，但这种活性是核糖核酸酶抑制的原因。
Other Notes
Thiol reagent. Carboxymethylation
Disclaimer
May discolor to yellowish on storage.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
[34a] carboxymethylation.
F R Gurd
Methods in enzymology, 25, 424-438 (1972-01-01)
Mirko Zaffagnini et al.
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Chiara Francavilla et al.
The Journal of cell biology, 187(7), 1101-1116 (2009-12-30)
Neural cell adhesion molecule (NCAM) associates with fibroblast growth factor (FGF) receptor-1 (FGFR1). However, the biological significance of this interaction remains largely elusive. In this study, we show that NCAM induces a specific, FGFR1-mediated cellular response that is remarkably different
Mia Jüllig et al.
PloS one, 9(5), e96489-e96489 (2014-05-08)
Bypass of foregut secreted factors promoting insulin resistance is hypothesized to be one of the mechanisms by which resolution of type 2 diabetes (T2D) follows roux-en-y gastric bypass (GBP) surgery. To identify insulin resistance-associated proteins and metabolites which decrease more
Elena B Lugli et al.
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Smoking is a well-established risk factor for rheumatoid arthritis (RA), and it has been proposed that smoking-induced citrullination renders autoantigens immunogenic. To investigate this mechanism, we examined human lung tissue from 40 subjects with defined smoking status, with or without
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