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Merck
CN

58240

靛红

for spectrophotometric det. of proline and thiophene, ≥99.0%

别名:

NSC 9262, 吲哚-2,3-二酮, 靛红

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关于此项目

经验公式(希尔记法):
C8H5NO2
化学文摘社编号:
分子量:
147.13
EC Number:
202-077-8
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
383659
MDL number:
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assay

≥99.0% (NT), ≥99.0%

quality

for spectrophotometric det. of proline and thiophene

technique(s)

UV/Vis spectroscopy: suitable

ign. residue

≤0.1%

loss

≤0.5% loss on drying

mp

193-195 °C (dec.) (lit.), 201-203 °C

SMILES string

O=C1Nc2ccccc2C1=O

InChI

1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)9-8(7)11/h1-4H,(H,9,10,11)

InChI key

JXDYKVIHCLTXOP-UHFFFAOYSA-N

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Other Notes

Reagent for the spectrophotometric det. of thiophene and proline

存储类别

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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An improved method for colorimetric determination of proline with isatin.
F N Boctor
Analytical biochemistry, 43(1), 66-70 (1971-09-01)
Franco Chimenti et al.
Bioorganic & medicinal chemistry, 18(14), 5063-5070 (2010-06-29)
The present study reports on synthesis in high yields (70-99%), HPLC enantioseparation, inhibitory activity against human monoamino oxidases, and molecular modeling including 3D-QSAR studies, of a large series of (4-aryl-thiazol-2-yl)hydrazones (1-45). Most of the synthesized compounds proved to be potent
Franco Chimenti et al.
Bioorganic & medicinal chemistry, 18(15), 5715-5723 (2010-07-10)
A new series of [4-(3-methoxyphenyl)-thiazol-2-yl]hydrazyne derivatives were synthesized in good yield (71-99%) and characterized by elemental analysis and (1)H NMR studies. The compounds were assayed for their in vitro human monoamine oxidase (hMAO) inhibitory activity and selectivity and most of
Hui Lv et al.
Organic letters, 14(21), 5412-5415 (2012-10-16)
An N-heterocyclic carbene (NHC)-catalyzed annulation reaction of isatin N-Boc ketimines and enals is developed for the synthesis of spirocyclic oxindole-γ-lactams bearing one quaternary chiral center in good yields and excellent stereoselectivities (up to >20:1 dr and 99% ee).
Alexandra Gaspar et al.
Journal of medicinal chemistry, 54(14), 5165-5173 (2011-06-24)
Two series of novel chromone derivatives were synthesized and investigated for their ability to inhibit the activity of monoamine oxidase. The SAR data indicate that chromone derivatives with substituents in position 3 of γ-pyrone nucleus act preferably as MAO-B inhibitors

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