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Merck
CN

59648

Sigma-Aldrich

(−)-Isoproterenol hydrochloride

≥98.0% (TLC)

别名:

(-)-异丙去甲肾上腺素 盐酸盐

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关于此项目

线性分子式:
3,4-(HO)2C6H3CH(OH)CH2NHCH(CH3)2·HCl
化学文摘社编号:
5984-95-2
分子量:
247.72
Beilstein:
6077193
MDL编号:
MFCD00064548
UNSPSC代码:
12352200

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方案

≥98.0% (TLC)

mp

175 °C (dec.) (lit.)

储存温度

−20°C

SMILES字符串

Cl[H].CC(C)NC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H/t11-;/m0./s1

InChI key

IROWCYIEJAOFOW-MERQFXBCSA-N

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生化/生理作用

β-adrenoceptor agonist; increases cytosolic cAMP.

其他说明

A β-adrenergic agonist. Regulation of protein phosphorylation by inotropic agents in isolated rat myocardial cells

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

预防措施声明

P261 - P305 + P351 + P338

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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分析证书(COA)

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Regulation of protein phosphorylation by inotropic agents in isolated rat myocardial cells.
J J Onorato et al.
The Journal of biological chemistry, 256(20), 10697-10703 (1981-10-25)
F Aura Kullmann et al.
The Journal of pharmacology and experimental therapeutics, 330(3), 704-717 (2009-06-12)
Voiding dysfunctions, including increased voiding frequency, urgency, or incontinence, are prevalent in the postmenopausal population. Beta(3)-adrenergic receptor (beta(3)AR) agonists, which relax bladder smooth muscle, are being developed to treat these conditions. We utilized the rat ovariectomy (OVX) model to investigate
Andreas Bock et al.
Cell, 182(6), 1519-1530 (2020-08-28)
Cells relay a plethora of extracellular signals to specific cellular responses by using only a few second messengers, such as cAMP. To explain signaling specificity, cAMP-degrading phosphodiesterases (PDEs) have been suggested to confine cAMP to distinct cellular compartments. However, measured
Chen-Cheng Lee et al.
Molecular cell, 76(3), 500-515 (2019-08-20)
Diet-induced obesity can be caused by impaired thermogenesis of beige adipocytes, the brown-like adipocytes in white adipose tissue (WAT). Promoting brown-like features in WAT has been an attractive therapeutic approach for obesity. However, the mechanism underlying beige adipocyte formation is

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