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Merck
CN

60890

Sigma-Aldrich

曲酸

purum, ≥98.0% (HPLC)

别名:

2-羟甲基-5-羟基-γ-吡喃酮, 5-羟基-2-羟甲基-4H-4-吡喃酮

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关于此项目

经验公式(希尔记法):
C6H6O4
化学文摘社编号:
分子量:
142.11
Beilstein:
120895
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
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等级

purum

方案

≥98.0% (HPLC)

mp

152-155 °C (lit.)

SMILES字符串

OCC1=CC(=O)C(O)=CO1

InChI

1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2

InChI key

BEJNERDRQOWKJM-UHFFFAOYSA-N

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生化/生理作用

酪氨酸酶抑制剂。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Edisson Tello et al.
Journal of natural products, 75(9), 1637-1642 (2012-08-22)
Three new cembranoid diterpenes, knightine (1), 11(R)-hydroxy-12(20)-en-knightal (2), and 11(R)-hydroxy-12(20)-en-knightol acetate (3), were isolated as minor constituents of the Caribbean gorgonian Eunicea knighti, along with the known cembranoids 4-8. The stereostructures of the new compounds were determined by detailed spectroscopic
Ya-Li Wang et al.
Journal of analytical methods in chemistry, 2018, 2141389-2141389 (2018-06-05)
Tyrosinase (TYR) is a rate-limiting enzyme in the synthesis of melanin, while direct TYR inhibitors are a class of important clinical antimelanoma drugs. This study established a spectrum-effect relationship analysis method and high-performance liquid chromatography-mass spectrometry (LC-MS) analysis method to
Ronald Bentley
Natural product reports, 23(6), 1046-1062 (2006-11-23)
This article reviews the curious history of kojic acid, discovered as a fungal natural product in 1907. It was one of the first secondary metabolites to have its biosynthetic pathway studied by the isotope tracer technique, and, more recently, has
Hyunjung Choi et al.
Journal of dermatological science, 66(3), 207-215 (2012-04-03)
Kojic acid is a fungal metabolite widely used in medicinal and cosmetic formulations as a skin-lightening agent based on its de-pigmenting activity. Although in human clinical studies kojic acid has been shown to be effective in the treatment of hyper-pigmentation
Ahmad Firdaus B Lajis et al.
Journal of biomedicine & biotechnology, 2012, 952452-952452 (2012-10-24)
The depigmenting effect of kojic acid esters synthesized by the esterification of kojic acid using Rhizomucor miehei immobilized lipase was investigated in B16F1 melanoma cells. The depigmenting effect of kojic acid and kojic acid esters was evaluated by the inhibitory

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