61382
2-羟基-D-谷氨酸 二钠盐
analytical standard
别名:
D-2HG, （R）-2-羟基戊二酸, （R）-2-羟基戊二酸二钠
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关于此项目
线性分子式:
C5H6O5Na2
化学文摘社编号:
分子量:
192.08
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
5318041
MDL number:
InChI
1S/C5H8O5.2Na/c6-3(5(9)10)1-2-4(7)8;;/h3,6H,1-2H2,(H,7,8)(H,9,10);;/q;2*+1/p-2/t3-;;/m1../s1
SMILES string
[Na].O[C@H](CCC(O)=O)C(O)=O
InChI key
DZHFTEDSQFPDPP-HWYNEVGZSA-L
grade
analytical standard
assay
≥98.0% (GC)
optical activity
[α]/D 8.5±1.5°, c = 1 in 0.1 M NaOH
shelf life
limited shelf life, expiry date on the label
application(s)
clinical testing
format
neat
storage temp.
2-8°C
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Application
D-α-羟基戊二酸二钠盐可用作分析标准，用于使用色谱法技术对异柠檬酸脱氢酶（IDH）突变肿瘤患者的人类血清样品中的2-羟基戊二酸（2HG）和2-羟基戊二酸（2HG）对映体的定量。
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Measurement of 2-hydroxyglutarate enantiomers in serum by chiral gas chromatography-tandem mass spectrometry and its application as a biomarker for IDH mutant gliomas
Strain KS, et al.
Clinical mass spectrometry, 15, 16-25 (2020)
Validation of a routine gas chromatography mass spectrometry method for 2-hydroxyglutarate quantification in human serum as a screening tool for detection of idh mutations
Fernandez-Galan E, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1083, 28-34 (2018)
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