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Merck
CN

61855

Sigma-Aldrich

L-亮氨酸胺 盐酸盐

purum, ≥99.0% (AT)

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线性分子式:
(CH3)2CHCH2CH(NH2)CONH2·HCl
化学文摘社编号:
分子量:
166.65
Beilstein:
4237021
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
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等级

purum

方案

≥99.0% (AT)

旋光性

[α]20/D +10±1°, c = 2% in H2O

光学纯度

enantiomeric ratio: ≥99:1 (GC)

mp

245-248 °C
254-256 °C (lit.)

应用

peptide synthesis

SMILES字符串

Cl.CC(C)C[C@H](N)C(N)=O

InChI

1S/C6H14N2O.ClH/c1-4(2)3-5(7)6(8)9;/h4-5H,3,7H2,1-2H3,(H2,8,9);1H/t5-;/m0./s1

InChI key

VSPSRRBIXFUMOU-JEDNCBNOSA-N

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其他说明

用于酸(作为混合酸酐)测定对映体比率的手性衍生化试剂

法规信息

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分析证书(COA)

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Measurement of carprofen enantiomer concentrations in plasma and urine using L-leucinamide as the chiral coupling component.
H Spahn et al.
Journal of chromatography, 433, 331-338 (1988-12-09)
Y L Wang et al.
Solid state nuclear magnetic resonance, 14(1), 19-32 (1999-07-17)
Proton NMR relaxation time measurements were carried out on solid tyrosine derivatives: acetyl-L-tyrosine ethyl ester (Ac-Tyroet), N-carbobenzyloxy-L-tyrosine ethyl ester (CBZ-Tyroet), N-trifluoroacetyl-L-tyrosine ethyl ester (TFAc-Tyroet) and their mixtures with L-leucinamide. It was found that spin-lattice relaxation was driven mainly by methyl
J C Hafkenscheid et al.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 23(7), 393-398 (1985-07-01)
A continuous procedure for the determination of leucine aminopeptidase is described. L-leucinamide is used as substrate and the liberated ammonia is determined with the glutamate dehydrogenase reaction. The enzyme is Mn2+-activated and 30 mumol/l MnCl2 is necessary for an optimal
Formation of diastereomeric derivatives of 2-arylpropionic acids using L-leucinamide: lack of generality.
R Mehvar et al.
Journal of chromatography, 431(1), 228-230 (1988-09-23)
Formation of diastereomeric derivatives of 2-arylpropionic acids using L-leucinamide.
H Spahn
Journal of chromatography, 423, 334-339 (1987-12-25)

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