61855
L-亮氨酸胺 盐酸盐
purum, ≥99.0% (AT)
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关于此项目
线性分子式:
(CH3)2CHCH2CH(NH2)CONH2·HCl
化学文摘社编号:
分子量:
166.65
EC Number:
233-952-2
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
4237021
MDL number:
InChI key
VSPSRRBIXFUMOU-JEDNCBNOSA-N
InChI
1S/C6H14N2O.ClH/c1-4(2)3-5(7)6(8)9;/h4-5H,3,7H2,1-2H3,(H2,8,9);1H/t5-;/m0./s1
SMILES string
Cl.CC(C)C[C@H](N)C(N)=O
grade
purum
assay
≥99.0% (AT)
optical activity
[α]20/D +10±1°, c = 2% in H2O
optical purity
enantiomeric ratio: ≥99:1 (GC)
mp
245-248 °C, 254-256 °C (lit.)
application(s)
peptide synthesis
Other Notes
用于酸（作为混合酸酐）测定对映体比率的手性衍生化试剂
法规信息
新产品
此项目有
Measurement of carprofen enantiomer concentrations in plasma and urine using L-leucinamide as the chiral coupling component.
H Spahn et al.
Journal of chromatography, 433, 331-338 (1988-12-09)
Y L Wang et al.
Solid state nuclear magnetic resonance, 14(1), 19-32 (1999-07-17)
Proton NMR relaxation time measurements were carried out on solid tyrosine derivatives: acetyl-L-tyrosine ethyl ester (Ac-Tyroet), N-carbobenzyloxy-L-tyrosine ethyl ester (CBZ-Tyroet), N-trifluoroacetyl-L-tyrosine ethyl ester (TFAc-Tyroet) and their mixtures with L-leucinamide. It was found that spin-lattice relaxation was driven mainly by methyl
J C Hafkenscheid et al.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 23(7), 393-398 (1985-07-01)
A continuous procedure for the determination of leucine aminopeptidase is described. L-leucinamide is used as substrate and the liberated ammonia is determined with the glutamate dehydrogenase reaction. The enzyme is Mn2+-activated and 30 mumol/l MnCl2 is necessary for an optimal
E A Permiakov et al.
Bioorganicheskaia khimiia, 28(1), 11-15 (2002-03-06)
The kinetics of the reaction of Boc-Xaa fluorophenyl esters (where Xaa = Ala, Val, Phe, Ser, Leu, Gly, Met, Pro, or Ile) with leucinamide was studied measuring changes in the fluorescence emission at 375 nm of the fluorophenyl chromophore accompanying
B R Madan et al.
Research communications in chemical pathology and pharmacology, 58(3), 393-396 (1987-12-01)
L-leucinamide hydrochloride, an amino acid derivative, was found to share the ability of phenylbutazone in attenuating the phlogistic response induced by intraplantar injection of formaldehyde and nystatin in the unanesthetized rat. In the granuloma pouch induced by the injection of
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