Merck
CN

64306

Sigma-Aldrich

甲基硫代磺酸甲酯

purum, ≥98.0% (GC)

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别名:
S-甲基硫代甲基砜, MMTS
线性分子式:
CH3SO2SCH3
CAS号:
分子量:
126.20
Beilstein:
1446059
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

等级

purum

质量水平

检测方案

≥98.0% (GC)

折射率

n20/D 1.513 (lit.)
n20/D 1.513

bp

69-71 °C/0.4 mmHg (lit.)

溶解性

chloroform: 750mg + 5 ml Chloroform mg/mL, colorless to light greenish-yellow

密度

1.337 g/mL at 20 °C
1.337 g/mL at 25 °C (lit.)

储存温度

2-8°C

SMILES字符串

CSS(C)(=O)=O

InChI

1S/C2H6O2S2/c1-5-6(2,3)4/h1-2H3

InChI key

XYONNSVDNIRXKZ-UHFFFAOYSA-N

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注意

储存时可能变为黄色

其他说明

亚甲基亚磺酰化剂有多种用途 ;对于 α-环酮的甲磺酰化 ;硫醇中的甲基二硫化物;酶的选择性、可逆性失活

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

188.6 °F - closed cup

闪点(°C)

87 °C - closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

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  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the solubility of Product 64306, S-Methyl methanethiosulfonate?

    Product 64306, S-Methyl methanethiosulfonate, is practically insoluble in water. It is soluble in methylene chloride. Several references do report that S-Methyl methanethiosulfonate is soluble in isopropanol at a 200mM concentration.  References are provided below: 1.  Yan, W., et al., "Quantitative Proteomic Analysis to Profile Dynamic Changes in the Spatial Distribution of Cellular Proteins", in Methods in Molecular Biology, Vol. 432: Organelle Proteomics, pp. 389-401 (Humana Press, 2008).2.  Sadowski, P.G., et al., Quantitative proteomic approach to study subcellular localization of membrane proteins.  Nature Protocols, 1, 1778-1789 (2006).

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

D. Scholz
Synthesis, 944-944 (1983)
P. Laszlo et al.
The Journal of Organic Chemistry, 49, 2281-2281 (1984)
Anna-Riikka Karala et al.
Antioxidants & redox signaling, 9(4), 527-531 (2007-02-07)
S-Methyl methanethiosulfonate (MMTS) is a reagent used to trap the natural thiol-disulfide state of the proteins. The efficiency of trapping mixed disulfides in vivo has been found to be higher for MMTS than for the more commonly used N-ethylmaleimide. MMTS
Decha Enkvetchakul et al.
The Journal of general physiology, 130(3), 329-334 (2007-08-19)
Interactions between nontransmembrane domains and the lipid membrane are proposed to modulate activity of many ion channels. In Kir channels, the so-called "slide-helix" is proposed to interact with the lipid headgroups and control channel gating. We examined this possibility directly
D J Smith et al.
Biochemistry, 14(4), 766-771 (1975-02-25)
New reagents for the temporary blocking of active or accessible sulfhydryl groups of enzymes have been developed. These reagents, which are either alkyl alkanethiolsulfonates or alkoxycarbonylalkyl disulfides, rapidly and quantitatively place various RS- groups on the sulfhydryls to generate mixed

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