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Merck
CN

67862

尿黑酸

analytical standard

别名:

2,5-二羟基苯乙酸

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线性分子式:
(HO)2C6H3CH2CO2H
化学文摘社编号:
分子量:
168.15
EC Number:
207-192-7
UNSPSC Code:
41116107
MDL number:
Beilstein/REAXYS Number:
2692860
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产品名称

尿黑酸, analytical standard

InChI key

IGMNYECMUMZDDF-UHFFFAOYSA-N

InChI

1S/C8H8O4/c9-6-1-2-7(10)5(3-6)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)

SMILES string

OC(=O)Cc1cc(O)ccc1O

grade

analytical standard

assay

≥98.0% (GC)

shelf life

limited shelf life, expiry date on the label

mp

150-152 °C (lit.)

application(s)

clinical testing

format

neat

storage temp.

2-8°C

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Application

Homogentisic acid may be used as an analytical reference standard for the quantification of the analyte in the following:
  • Urine matrices using reversed-phase liquid chromatography tandem mass spectrometry (LC-MS/MS).
  • Strawberry tree honey samples using reversed phase-high performance liquid chromatography (RP-HPLC) and ion chromatography (IC).

It may also be used as an internal standard for the determination of ascorbic acid (AA) and uric acid (UA) in human plasma samples using high-pressure liquid chromatography–electrochemical detection (HPLC–ECD).

General description

Homogentisic acid is a marker of the botanic origin of strawberry tree honey.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Fast HPLC?ECD analysis of ascorbic acid, dehydroascorbic acid and uric acid
Li X, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(10), 853-856 (2009)
Direct chromatographic methods for the rapid determination of homogentisic acid in strawberry tree (Arbutus unedo L.) honey
Scanu R, et al.
Journal of Chromatography A, 1090(1-2), 76-80 (2005)
Urine homogentisic acid and tyrosine: simultaneous analysis by liquid chromatography tandem mass spectrometry
Hughes TA, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 963, 106-112 (2014)

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