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经验公式(希尔记法):
C24H30O11
化学文摘社编号:
分子量:
494.49
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
EC Number:
242-881-6
MDL number:
InChI key
KVRQGMOSZKPBNS-FMHLWDFHSA-N
InChI
1S/C24H30O11/c1-23(35-16(27)8-7-13-5-3-2-4-6-13)11-15(26)24(31)9-10-32-22(20(23)24)34-21-19(30)18(29)17(28)14(12-25)33-21/h2-10,14-15,17-22,25-26,28-31H,11-12H2,1H3/b8-7+/t14-,15-,17-,18+,19-,20-,21+,22+,23+,24-/m1/s1
SMILES string
C[C@@]1(C[C@@H](O)[C@]2(O)C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]12)OC(=O)\C=C\c4ccccc4
grade
analytical standard
assay
≥95.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
Quality Level
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General description
Harpagoside, a naturally occurring iridoid glycoside, is the main bioactive component of medicinal plants like Radix Scrophulariae, Scrophularia ningpoensis, Scrophularia buergeriana and Harpagophytum procumbens. It can exhibit a wide range of biological and pharmacological properties and hence used in the treatment of ailments like pharyngalgia, arthritis, rheumatism, tussis and constipation.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Harpagoside: from Kalahari Desert to pharmacy shelf
Georgiev.IM, et al.
Phytochemistry, 92, 8-15 (2013)
Simultaneous determination of harpagoside and cinnamic acid in rat plasma by high-performance liquid chromatography: application to a pharmacokinetic study
Li P, et al.
Analytical and Bioanalytical Chemistry, 389, 2259-2264 (2007)
Nadia Romiti et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 16(12), 1095-1100 (2009-07-07)
Devil's Claw (Harpagophytum procumbens) a plant native to Southern Africa, has historically been used in traditional medicine to treat a wide range of diseases and currently is widely employed as anti-inflammatory and pain-relieving natural remedy in Europe and other parts
Jinfeng Tian et al.
Journal of separation science, 35(19), 2659-2664 (2012-09-25)
In this study, the bioactive component harpagoside and angroside C in the root of Scrophularia ningpoensis Hemsley was simultaneously separated by high-speed counter-current chromatography (HSCCC). A two-phase solvent system containing chloroform/n-butanol/methanol/water (4:1:3:2, v/v/v/v) was selected following consideration of the partition
Corinna Boeckenholt et al.
Planta medica, 78(8), 761-766 (2012-03-14)
Silymarin and harpagoside are derived from drugs which are used for their protective effects against hepatotoxicity and inflammatory processes. Both are now investigated with respect to the respiratory tract. They were able to reduce the release of the inflammatory cytokine
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