68923
七叶亭
analytical standard
别名:
6,7-二羟基香豆素, 七叶亭, 秦皮乙素
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关于此项目
经验公式（希尔记法）:
C9H6O4
化学文摘社编号:
分子量:
178.14
UNSPSC Code:
12352200
NACRES:
NA.24
PubChem Substance ID:
EC Number:
206-161-5
Beilstein/REAXYS Number:
152788
MDL number:
SMILES string
Oc1cc2OC(=O)C=Cc2cc1O
InChI
1S/C9H6O4/c10-6-3-5-1-2-9(12)13-8(5)4-7(6)11/h1-4,10-11H
InChI key
ILEDWLMCKZNDJK-UHFFFAOYSA-N
grade
analytical standard
assay
≥97.5% (HPLC), 97.5-102.5% (NT)
shelf life
limited shelf life, expiry date on the label
mp
271-273 °C (lit.)
format
neat
Quality Level
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General description
秦皮乙素是香豆素衍生物，存在于多种植物中，包括菊苣（ Cichorium intybus ）（菊苣）、三角梅（ Bougainvillea spectabilis），茵陈蒿（ Artemisia capillaris）等植物，还存在于柠檬（ Citrus limonia ）（芸香科），紫金莲（ Ceratostigma willmottianumum）等的叶片中。具有多种药理活性，被认为是环氧合酶、5-脂氧合酶、12-脂氧合酶，儿茶酚-O-甲基转移酶，NADPH氧化酶和黄嘌呤氧化酶的强效抑制剂。
Application
秦皮乙素可用作分析参考标准品，通过色谱技术测定生物样品 和水样 中的分析物。也可作为标准品，分别通过固相萃取和胶束电动毛细管法，定量传统草药中的分析物 。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Esculetin prevents liver damage induced by paracetamol and CCl4
Gilani AH, et al.
Pharmacological Research, 37(1), 31-35 (1998)
Determination of polyphenol components in herbal medicines by micellar electrokinetic capillary chromatography with Tween 20
Wang XK, et al.
Talanta, 74(1), 1-6 (2007)
Solid-phase extraction of esculetin from the ash bark of Chinese traditional medicine by using molecularly imprinted polymers
Hu SG, et al.
Journal of Chromatography A, 1062(1), 31-37 (2005)
Inhibition of cell cycle progression in human leukemia HL-60 cells by esculetin
Wang CJ, et al.
Cancer Letters, 183(2), 163-168 (2002)
Cristina Mesas et al.
Nutrients, 13(2) (2021-02-13)
The seeds of Euphorbia lathyris have been used in traditional medicine to treat various medical conditions. However, neither all of their active biocompounds nor the molecular mechanisms underlying their therapeutic effects have been described. A new ethanolic extract of defatted
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