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Merck
CN

69575

O-Methyl-D-tyrosine

≥99.0% (NT)

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经验公式(希尔记法):
C10H13NO3
化学文摘社编号:
分子量:
195.22
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
3201704
MDL number:
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assay

≥99.0% (NT)

optical activity

[α]20/D +7.0±1°, c = 1% in 5 M HCl

SMILES string

COc1ccc(C[C@@H](N)C(O)=O)cc1

InChI

1S/C10H13NO3/c1-14-8-4-2-7(3-5-8)6-9(11)10(12)13/h2-5,9H,6,11H2,1H3,(H,12,13)/t9-/m1/s1

InChI key

GEYBMYRBIABFTA-SECBINFHSA-N

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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T Ashton Cropp et al.
Nature protocols, 2(10), 2590-2600 (2007-10-20)
The genetic code of living organisms has been expanded to allow the site-specific incorporation of unnatural amino acids into proteins in response to the amber stop codon UAG. Numerous amino acids have been incorporated including photo-crosslinkers, chemical handles, heavy atoms
Jeffrey K Takimoto et al.
ACS chemical biology, 6(7), 733-743 (2011-05-07)
Unnatural amino acids (Uaas) can be translationally incorporated into proteins in vivo using evolved tRNA/aminoacyl-tRNA synthetase (RS) pairs, affording chemistries inaccessible when restricted to the 20 natural amino acids. To date, most evolved RSs aminoacylate Uaas chemically similar to the
Sebastian M Kuhn et al.
Journal of molecular biology, 404(1), 70-87 (2010-09-15)
We describe a strategy for the rapid selection of mutant aminoacyl-tRNA synthetases (aaRS) with specificity for a novel amino acid based on fluorescence-activated cell sorting of transformed Escherichia coli using as reporter the enhanced green fluorescent protein (eGFP) whose gene
Ning Wu et al.
Journal of the American Chemical Society, 126(44), 14306-14307 (2004-11-04)
We have developed a second orthogonal tRNA/synthetase pair for use in yeast based on the Escherichia coli tRNALeu/leucyl tRNA-synthetase pair. Using a novel genetic selection, we have identified a series of synthetase mutants that selectively charge the amber suppresor tRNA
Molecular biology. Invading the genetic code.
A Böck
Science (New York, N.Y.), 292(5516), 453-454 (2001-05-02)

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