69761
3,5-二羟基-3-甲基戊酸内酯
purum, ≥96.0% (T)
别名:
(±)-3-羟基-3-甲基 δ-戊内酯, (±)-β-羟基-β-甲基-δ-戊内酯, DL-甲羟戊酸内酯
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关于此项目
经验公式（希尔记法）:
C6H10O3
化学文摘社编号:
分子量:
130.14
EC Number:
211-615-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
80960
MDL number:
InChI key
JYVXNLLUYHCIIH-UHFFFAOYSA-N
InChI
1S/C6H10O3/c1-6(8)2-3-9-5(7)4-6/h8H,2-4H2,1H3
SMILES string
CC1(O)CCOC(=O)C1
grade
purum
assay
≥96.0% (T)
impurities
salt, none detected
mp
24-27 °C
storage temp.
2-8°C
Other Notes
Lactone of mevalonic acid which is a very important connecting link in the biosynthesis of isoprenoids
Disclaimer
can form fused mass at low temperatures
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
The biosynthesis of cholesterol.
G POPJAK et al.
Advances in enzymology and related subjects of biochemistry, 22, 281-335 (1960-01-01)
J.W. Porter et al.
Biosynthesis of Isoprenoid Compounds, vol. 1 and 2 null
B. Preiss, ed.
Regulation of HMG-CoA Reductase null
R. Clayton
Quart. Rev., 19, 168-168 (1965)
Martha M Monick et al.
Journal of immunology (Baltimore, Md. : 1950), 171(5), 2625-2630 (2003-08-21)
These studies demonstrate that treatment of macrophages with lovastatin, a cholesterol-lowering drug that blocks farnesylation and geranylgeranylation of target proteins, increases LPS-induced TNF-alpha production. This is reversed by the addition of mevalonate, which bypasses the lovastatin block. Examination of membrane
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