70015
蝇蕈醇
别名:
3-羟基-5-氨甲基-异噁唑, 5-氨甲基-3-异噁唑醇, 5-氨甲基-3-羟基-异噁唑, Pantherine, 毒蝇蕈醇
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关于此项目
经验公式（希尔记法）:
C4H6N2O2
化学文摘社编号:
分子量:
114.10
EC Number:
220-430-4
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
1618960
MDL number:
InChI key
ZJQHPWUVQPJPQT-UHFFFAOYSA-N
InChI
1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)
SMILES string
NCC1=CC(=O)NO1
Gene Information
rat ... Gabra2(29706)
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Biochem/physiol Actions
GABAA受体激动剂。
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - STOT SE 3
target_organs
Central nervous system
存储类别
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Pierre Le Merre et al.
Neuron, 97(1), 83-91 (2017-12-19)
The neural circuits underlying learning and execution of goal-directed behaviors remain to be determined. Here, through electrophysiological recordings, we investigated fast sensory processing across multiple cortical areas as mice learned to lick a reward spout in response to a brief
Jette G Petersen et al.
Journal of medicinal chemistry, 56(3), 993-1006 (2013-01-09)
A series of bioisosteric 4-(aminomethyl)-1-hydroxypyrazole (4-AHP) analogues of muscimol, a GABA(A) receptor agonist, has been synthesized and pharmacologically characterized at native and selected recombinant GABA(A) receptors. The unsubstituted 4-AHP analogue (2a) (EC(50) 19 μM, R(max) 69%) was a moderately potent
Tora Bonnevie et al.
Nature neuroscience, 16(3), 309-317 (2013-01-22)
To determine how hippocampal backprojections influence spatially periodic firing in grid cells, we recorded neural activity in the medial entorhinal cortex (MEC) of rats after temporary inactivation of the hippocampus. We report two major changes in entorhinal grid cells. First
Binsing studies with muscimol; relation ty synaptic gamma-aminobutyrate receptors.
F V DeFeudis
Neuroscience, 5(4), 675-688 (1980-01-01)
Muscimol, a psychoactive constituent of Amanita muscaria, as a medicinal chemical model structure.
P Krogsgaard-Larsen et al.
Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 35(5), 311-324 (1981-01-01)
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