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Merck
CN

73339

愈甘醚

pharmaceutical secondary standard; traceable to USP and PhEur

别名:

愈创木酚甘油基醚, 3-(o-甲氧基苯氧基)-1,2-丙二醇, 愈创甘油醚, 甘油愈创木酯

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经验公式(希尔记法):
C10H14O4
化学文摘社编号:
分子量:
198.22
EC Number:
202-222-5
UNSPSC Code:
41116000
MDL number:
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agency

traceable to Ph. Eur. G0700000, traceable to USP 1301007

SMILES string

COc1ccccc1OCC(O)CO

InChI

1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3

InChI key

HSRJKNPTNIJEKV-UHFFFAOYSA-N

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

13 - Non Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Robert J Brosnan et al.
American journal of veterinary research, 72(12), 1569-1575 (2011-12-01)
To evaluate whether guaifenesin can prevent adverse anesthetic induction events caused by propofol and whether a guaifenesin-propofol induction combination has brief cardiovascular effects commensurate with rapid drug washout. 8 healthy adult horses. Guaifenesin was administered IV for 3 minutes followed
JeanClare Seagrave et al.
Experimental lung research, 37(10), 606-614 (2011-11-03)
Guaifenesin is widely used to alleviate symptoms of excessive mucus accumulation in the respiratory tract. However, its mechanism of action is poorly understood. The authors hypothesized that guaifenesin improves mucociliary clearance in humans by reducing mucin release, by decreasing mucus
Mehdi Hatami et al.
Biomedical chromatography : BMC, 26(7), 875-880 (2011-11-22)
A hollow fiber liquid-phase microextraction technique coupled with high-performance liquid chromatography with fluorescence detection was employed for determination and evaluation of the binding characteristics of drugs to bovine serum albumin (BSA). Enantiomers of guaifenesin (an expectorant drug) were investigated as
Helmut Albrecht et al.
Respiratory research, 13, 118-118 (2012-12-29)
Guaifenesin is a component of medicines used to improve symptoms associated with upper respiratory tract infections. Patient-reported outcome instruments are valuable for evaluating symptom improvements; however, a validated tool to assess efficacy of mucoactive drugs does not exist. We compared
Mehdi Hatami et al.
Journal of separation science, 34(21), 2933-2939 (2011-10-06)
A simple, rapid, and efficient method, dispersive liquid-liquid microextraction (DLLME) coupled with high-performance liquid chromatography-fluorescence detector, has been developed for the determination of guaifenesin (GUA) enantiomers in human urine samples after an oral dose administration of its syrup formulation. Urine

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