73390
2-硝基咪唑
purum, ≥98.0% (HPLC)
别名:
吖素
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关于此项目
经验公式（希尔记法）:
C3H3N3O2
化学文摘社编号:
分子量:
113.07
EC Number:
208-425-5
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
116444
MDL number:
grade
purum
assay
≥98.0% (HPLC)
mp
287 °C (dec.) (lit.)
SMILES string
[O-][N+](=O)c1ncc[nH]1
InChI
1S/C3H3N3O2/c7-6(8)3-4-1-2-5-3/h1-2H,(H,4,5)
InChI key
YZEUHQHUFTYLPH-UHFFFAOYSA-N
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
Piyush Kumar et al.
Bioorganic & medicinal chemistry letters, 18(11), 3256-3260 (2008-05-16)
Stereospecific synthesis of 1-alpha-d-(2-deuteroribofuranosyl)-2-nitroimidazole (2'-[(2)H]-alpha-AZR) is reported. This, deuteration was independent of the configuration of C-2' -OH group (arabinose or ribose) in sugar moiety of starting molecules. Slightly better yield (>37%) of the deuterated product, 6, from arabinosyl precursor in
Radiation-induced oxidative denitration of 2-nitroimidazoles in aqueous solution.
H Ide et al.
Journal of radiation research, 25(3), 246-250 (1984-09-01)
M E Watts et al.
International journal of radiation biology and related studies in physics, chemistry, and medicine, 47(6), 645-653 (1985-06-01)
The effect of extracellular pH (pHe) on the radiosensitization of hypoxic Chinese hamster V79 cells in vitro by the 2-nitroimidazole, misonidazole, and analogues substituted with basic or acid functions has been studied. Misonidazole (1 mmol dm-3) gave an enhancement ratio
M E Watts et al.
International journal of radiation biology, 57(2), 361-372 (1990-02-01)
The radiosensitization of two human tumour in vitro cell lines, HT-1080 and LoVo, has been compared with that of the Chinese hamster cell line V79-379A. Although the two human tumour cell lines were more radiosensitive than the V79 cell line
P Kumar et al.
Medicinal chemistry (Shariqah (United Arab Emirates)), 5(2), 118-129 (2009-03-12)
(18)F-Labelled fluoroazomycin arabinoside ([(18)F]FAZA) is a 2-nitroimidazole (azomycin) based PET tracer used extensively in cancer clinics to diagnose tumour hypoxia. The hypoxia-specific uptake and rapid blood clearance kinetics of FAZA contribute to good tumor-to-background ratios (T/B ratios) and high image
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