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Merck
CN

73780

3-硝基邻苯二甲酸酐

purum, ≥96.0% (NT)

别名:

3-Nitrophthalic acid anhydride, 4-Nitro-2-benzofuran-1,3-dione, 4-Nitroisobenzofuran-1,3-dione

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关于此项目

经验公式(希尔记法):
C8H3NO5
化学文摘社编号:
分子量:
193.11
EC Number:
211-373-6
UNSPSC Code:
12162002
PubChem Substance ID:
Beilstein/REAXYS Number:
179963
MDL number:
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InChI key

ROFZMKDROVBLNY-UHFFFAOYSA-N

InChI

1S/C8H3NO5/c10-7-4-2-1-3-5(9(12)13)6(4)8(11)14-7/h1-3H

SMILES string

[O-][N+](=O)c1cccc2C(=O)OC(=O)c12

grade

purum

assay

≥96.0% (NT)

mp

162-165 °C, 163-165 °C (lit.)

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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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分析证书(COA)

Lot/Batch Number

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Koichiro Teshima et al.
Journal of pharmaceutical and biomedical analysis, 47(3), 560-566 (2008-03-04)
A liquid chromatography-tandem mass spectrometric (LC-MS/MS) method following chemical derivatization with 3-nitrophtalic anhydride was developed for the simultaneous determination of farnesol and geranylgeraniol in rat liver and testis. One analogue compound of the analytes, n-pentadecanol, was used as an internal
M Pawlowska et al.
Journal of chromatography. A, 666(1-2), 485-491 (1994-04-22)
New pre-column derivatizing reagents: phthalic anhydride, 3-nitrophthalic anhydride, diphenic anhydride, 1,8-naphthalic anhydride and diphenylmaleic anhydride have been developed for resolving chiral compounds having amine groups. Although all of these agents produce derivatives with high molar absorptivities, the later two also
Mauro Vieira de Almeida et al.
Chemical & pharmaceutical bulletin, 55(2), 223-226 (2007-02-03)
Fourteen thalidomide analogs bearing two phthalimido units were prepared in high yields (83-94%) by condensation of different diamines with phthalic or 3-nitrophthalic anhydride. An in vitro investigation of the compounds as inhibitors of the TNF-alpha production was performed. The inhibition

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