75320
Okadaic acid
≥92% (HPLC)
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关于此项目
经验公式（希尔记法）:
C44H68O13
化学文摘社编号:
分子量:
805.00
UNSPSC Code:
12352202
MDL number:
Beilstein/REAXYS Number:
4640246
assay
≥92% (HPLC)
storage temp.
2-8°C
SMILES string
[H][C@@]1(CC[C@@]2(CC[C@@]3([H])O[C@]([H])([C@@H](O)C[C@H](C)[C@@]4([H])O[C@@]5(CCCCO5)CC[C@H]4C)C(=C)[C@@H](O)[C@]3([H])O2)O1)\C=C\[C@@H](C)[C@]6([H])CC(C)=C[C@@]7(O[C@@H](CC[C@H]7O)C[C@@](C)(O)C(O)=O)O6
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General description
Marine toxin, produced by dinoflagellates, accumulates in bivalves and sponges.
Other Notes
This product has been replaced by O4511-SIGMA | Okadaic acid from Prorocentrum concavum ≥90% (HPLC), translucent film
Tumour promoter and specific inhibitor of protein phosphatases 1 and 2A, review
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Beatriz Aranda-Orgillés et al.
PloS one, 3(10), e3507-e3507 (2008-10-25)
Mutations in the MID1 protein have been found in patients with Opitz BBB/G syndrome (OS), which is characterised by multiple malformations of the ventral midline. MID1 is a microtubule-associated protein that stabilizes microtubules and, in association with the regulatory subunit
Stuart T Perry et al.
PLoS pathogens, 7(2), e1001297-e1001297 (2011-03-08)
Dengue virus (DENV) is a mosquito-borne flavivirus, and symptoms of infection range from asymptomatic to the severe dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). High viral loads correlate with disease severity, and both type I & II interferons (IFNs) are crucial
P Cohen et al.
Trends in biochemical sciences, 15(3), 98-102 (1990-03-01)
The tumour promoter okadaic acid is a potent and specific inhibitor of protein phosphatases 1 and 2A. Here we review recent studies which demonstrate that this toxin is extremely useful for identifying biological processes that are controlled through the reversible
M A Battistone et al.
Molecular human reproduction, 19(9), 570-580 (2013-05-01)
In all mammalian species studied so far, sperm capacitation correlates with an increase in protein tyrosine (Tyr) phosphorylation mediated by a bicarbonate-dependent cAMP/protein kinase A (PKA) pathway. Recent studies in mice revealed, however, that a Src family kinase (SFK)-induced inactivation
J J Fernández et al.
Current medicinal chemistry, 9(2), 229-262 (2002-02-28)
One of the most interesting groups of substances of marine origin, from structural and pharmacological points of view are polyether toxins, which generally present a great diversity in size and potent biological activities. The subject of this review is limited
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 345415-25G | 04061836684624 |
| 345415-5G | 04061836684631 |
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