InChI key
FDGQSTZJBFJUBT-UHFFFAOYSA-N
InChI
1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
SMILES string
O=C1NC=Nc2nc[nH]c12
biological source
synthetic
assay
≥99.0% (HPLC), 98.0-101.0% (wt%, HClO4 1M, NT)
form
powder
impurities
≤2 wt. % water, ≤20 mg/kg heavy metals, ≤5000 mg/kg residual solvents (acetone) (GLC-HS), ≤5000 mg/kg residual solvents (isopropanol) (GLC-HS)
mp
>300 °C (lit.)
suitability
suitable for manufacturing use
Quality Level
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Application
次黄嘌呤是一种营养添加剂,适用于细菌、寄生虫(恶性疟原虫)和动物细胞等多种细胞培养应用。 次黄嘌呤是杂交瘤技术所用选择培养基的组分。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Tomáš Tichý et al.
European journal of medicinal chemistry, 55, 307-314 (2012-08-04)
Hexadecyloxypropyl esters of acyclic nucleoside phosphonates containing guanine (G) or hypoxanthine (Hx) and a (S)-[3-hydroxy-2-(phosphonomethoxy)propyl] [(S)-HPMP] or 2-(2-phosphonoethoxy)ethyl (PEE) acyclic moiety have been prepared. The activity of the prodrugs was evaluated in vitro against different virus families. Whereas ester derivatives of
Abdulazeez T Lawal et al.
Food chemistry, 135(4), 2982-2987 (2012-09-18)
A potentiometric enzyme electrode for detection of hypoxanthine (Hx) in fish meat is described. The sensor was developed by entrapment of xanthine oxidase (XOD) and ferrocene carboxylic acid (Fc) into polypyrrole (PPy) film during galvanostatic polymerisation film formation. The responses
Chia-Tung Wu et al.
Cardiovascular research, 102(3), 487-496 (2014-03-07)
Fibroblasts, which play an important role in cardiac function/dysfunction, including arrhythmogenesis, have voltage-dependent (Kv) currents of unknown importance. Here, we assessed the differential expression of Kv currents between atrial and ventricular fibroblasts from control dogs and dogs with an atrial
Chien-Wei Hou et al.
The American journal of Chinese medicine, 40(5), 979-991 (2012-08-30)
Hyperuricemia causes gouty arthritis, kidney disease, heart disease, and other diseases. Xanthine oxidase (XOD) and urate transporters play important roles in urate homeostasis. Numerous plants have been identified as XOD inhibitors. Longan seeds are known to contain high levels of
Cristina Müller et al.
Molecular pharmaceutics, 10(3), 967-974 (2013-02-12)
Folate receptor (FR) targeting is an attractive strategy for nuclear imaging of cancer and activated macrophages through application of folic acid radioconjugates. However, significant renal accumulation of folate radioconjugates and hence exceedingly high emission of radiation from the kidneys may
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