77790
酚妥拉明 盐酸盐
≥99.0% (TLC)
别名:
2-[N-（3-羟基苯基）-对-甲苯胺基甲基] -2-咪唑烷 盐酸盐, 3-[[（4,5-二氢-1H-咪唑-2-基）- 甲基]（4-甲基苯基）-氨基]-苯酚 单盐酸盐
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关于此项目
经验公式（希尔记法）:
C17H19N3O · HCl
化学文摘社编号:
分子量:
317.81
EC Number:
200-793-5
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
3764617
assay
≥99.0% (TLC)
solubility
methanol: 10 mg/mL, clear, colorless
SMILES string
Cl[H].Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3
InChI
1S/C17H19N3O.ClH/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H
InChI key
TUEJFGFQYKDAPM-UHFFFAOYSA-N
Application
α-Adrenergic blocker
Biochem/physiol Actions
α-肾上腺素能受体拮抗剂；外周血管扩张剂。
法规信息
新产品
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Wei Peng et al.
Journal of photochemistry and photobiology. B, Biology, 171, 75-84 (2017-05-10)
Phentolamine is one of the most representative nonselective α-adrenoreceptor blocking agents, which have been proved to be owned various pharmacological actions. Unfortunately, whether erythrocytes in the veins intervene in biological behaviors of such drug are largely obscured. With the aid
S Morishima et al.
British journal of pharmacology, 153(7), 1485-1494 (2008-01-29)
In addition to alpha1A, alpha1B and alpha1D-adrenoceptors (ARs), putative alpha1L-ARs with a low affinity for prazosin have been proposed. The purpose of the present study was to identify the alpha1A-AR and clarify its pharmacological profile using a radioligand binding assay.
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