78645
左乙拉西坦
analytical standard
别名:
(αS)-α-乙基-2-氧代-1-吡咯烷乙酰胺, 2（S）-（2-氧吡咯烷-1-基）丁酰胺
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选择尺寸
关于此项目
经验公式（希尔记法）:
C8H14N2O2
化学文摘社编号:
分子量:
170.21
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C8H14N2O2/c1-2-6(8(9)12)10-5-3-4-7(10)11/h6H,2-5H2,1H3,(H2,9,12)/t6-/m0/s1
SMILES string
CC[C@H](N1CCCC1=O)C(N)=O
InChI key
HPHUVLMMVZITSG-LURJTMIESA-N
grade
analytical standard
assay
≥98.0% (HPLC)
optical activity
[α]/D -90±5°, c = 1 in acetone
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
veterinary
format
neat
Quality Level
Gene Information
human ... CACNA1B(774), SV2A(9900)
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General description
左乙拉西坦是一种口服活性抗癫痫药，具有较高的治疗指数，以及抗癫痫药和抗惊厥的潜力。
Application
使用高效液相色谱-电喷雾串联质谱法（HPLC-ESI-MS/MS）测定生物流体样品中的左乙拉西坦时，左乙拉西坦可作为参考标准品。
有关合适的仪器技术的更多信息，请参阅产品的分析证书。想要获得更多支持，请联系技术服务部。
Biochem/physiol Actions
左乙拉西坦是一种具有抗癫痫活性的吡咯烷。
左乙拉西坦是一种具有抗癫痫活性的吡咯烷。左乙拉西坦的立体选择性结合仅限于中枢神经系统的突触质膜，而在周围组织中不发生立体选择性结合。左乙拉西坦在不影响正常神经元兴奋性的情况下抑制簇状放电，这表明它可以选择性地阻止癫痫样簇状放电的超同步和发作活动的传播。
Other Notes
在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析（使用数字化外标）。可查看该物质的NMR谱图，只需点击几次鼠标，就能进行在线样品比对。欢迎点击了解更多，开启免费试用之旅。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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