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Merck
CN

79715

O-磷酸-L-丝氨酸

~95% (TLC)

别名:

L-2-氨基-3-羟基丙酸3-磷酸, L-SOP, L-丝氨酸O-磷酸

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关于此项目

线性分子式:
(HO)2P(O)OCH2CH(NH2)CO2H
化学文摘社编号:
分子量:
185.07
EC Number:
206-986-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
1726826
MDL number:
eCl@ss:
32160406
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assay

~95% (TLC)

impurities

≤2% water

mp

190 °C (lit.)

solubility

H2O: 50 mg/mL, clear, colorless to slightly yellow (hot)

SMILES string

N[C@@H](COP(O)(O)=O)C(O)=O

InChI

1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1

InChI key

BZQFBWGGLXLEPQ-REOHCLBHSA-N

Biochem/physiol Actions

III 组亲代谢型谷氨酸受体激动剂(mGluR4、mGluR7 和 mGluR8)。


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pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

存储类别

8B - Non-combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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S A Kang-Yoon et al.
The American journal of clinical nutrition, 55(4), 865-872 (1992-04-01)
Pyridoxal 5'-phosphate (PLP) is a coenzyme in many metabolic transformations of amino acids and may play a role in their absorption and transport. This investigation analyzed the effects of large oral doses (27 mg/d) of pyridoxine (PN)-HCl over 2 wk
Geneviève Desjardins et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(30), 11019-11024 (2014-07-16)
The E26 transformation-specific (Ets-1) transcription factor is autoinhibited by a conformationally disordered serine-rich region (SRR) that transiently interacts with its DNA-binding ETS domain. In response to calcium signaling, autoinhibition is reinforced by calmodulin-dependent kinase II phosphorylation of serines within the
R P Hulse et al.
Neurobiology of disease, 71, 245-259 (2014-08-26)
Vascular endothelial growth factor-A (VEGF-A) is best known as a key regulator of the formation of new blood vessels. Neutralization of VEGF-A with anti-VEGF therapy e.g. bevacizumab, can be painful, and this is hypothesized to result from a loss of