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Merck
CN

79715

O-磷酸-L-丝氨酸

~95% (TLC)

别名:

L-2-氨基-3-羟基丙酸3-磷酸, L-SOP, L-丝氨酸O-磷酸

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关于此项目

线性分子式:
(HO)2P(O)OCH2CH(NH2)CO2H
化学文摘社编号:
分子量:
185.07
EC Number:
206-986-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
1726826
MDL number:
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InChI key

BZQFBWGGLXLEPQ-REOHCLBHSA-N

InChI

1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1

SMILES string

N[C@@H](COP(O)(O)=O)C(O)=O

assay

~95% (TLC)

impurities

≤2% water

mp

190 °C (lit.)

solubility

H2O: 50 mg/mL, clear, colorless to slightly yellow (hot)

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Biochem/physiol Actions

III 组亲代谢型谷氨酸受体激动剂(mGluR4、mGluR7 和 mGluR8)。

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

存储类别

8B - Non-combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J N Verma et al.
Journal of lipid research, 26(5), 610-616 (1985-05-01)
Phosphatidylserine decarboxylase activity has been characterized in membrane preparations from Clostridium butyricum ATCC 19398. A particulate fraction was shown to catalyze the formation of phosphatidylethanolamine and plasmenylethanolamine when vesicles containing phosphatidylserine and plasmenylserine were used as substrate. No plasmenylethanolamine was
Geneviève Desjardins et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(30), 11019-11024 (2014-07-16)
The E26 transformation-specific (Ets-1) transcription factor is autoinhibited by a conformationally disordered serine-rich region (SRR) that transiently interacts with its DNA-binding ETS domain. In response to calcium signaling, autoinhibition is reinforced by calmodulin-dependent kinase II phosphorylation of serines within the
R P Hulse et al.
Neurobiology of disease, 71, 245-259 (2014-08-26)
Vascular endothelial growth factor-A (VEGF-A) is best known as a key regulator of the formation of new blood vessels. Neutralization of VEGF-A with anti-VEGF therapy e.g. bevacizumab, can be painful, and this is hypothesized to result from a loss of
Latha Ramalingam et al.
Diabetologia, 57(7), 1476-1484 (2014-04-08)
Insulin secretion from pancreatic beta cells and insulin-stimulated glucose uptake into skeletal muscle are processes regulated by similar isoforms of the soluble N-ethylmaleimide-sensitive factor-attachment protein receptor (SNARE) and mammalian homologue of unc-18 (Munc18) protein families. Double C2 domain β (Doc2b)
S A Kang-Yoon et al.
The American journal of clinical nutrition, 55(4), 865-872 (1992-04-01)
Pyridoxal 5'-phosphate (PLP) is a coenzyme in many metabolic transformations of amino acids and may play a role in their absorption and transport. This investigation analyzed the effects of large oral doses (27 mg/d) of pyridoxine (PN)-HCl over 2 wk

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