InChI
1S/C14H16O9/c1-21-11-5(16)2-4-7(9(11)18)12-13(23-14(4)20)10(19)8(17)6(3-15)22-12/h2,6,8,10,12-13,15-19H,3H2,1H3/t6-,8-,10+,12+,13-/m1/s1
InChI key
YWJXCIXBAKGUKZ-HJJNZUOJSA-N
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤10.0% water
application(s)
food and beverages
format
neat
storage temp.
2-8°C
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Xuan Qin et al.
Acta pharmacologica Sinica, 31(1), 127-136 (2009-12-08)
To prepare a bergenin-phospholipid complex (BPC) to increase oral bioavailability of the drug. In order to obtain the acceptable BPC, a spherical symmetric design-response surface methodology was used for process optimization. The influence of reaction medium, temperature, drug concentration and
Rajesh Kumar et al.
Fitoterapia, 83(2), 395-401 (2011-12-20)
Bergenin, a major constituent of Caesalpinia digyna Rottler (Leguminosae) was isolated from its roots and was characterized by comparing its melting point and spectroscopic data (IR, (1)H, (13)C, Mass Spectra) with standard bergenin. Isolated bergenin was then evaluated for antidiabetic
Umang Singh et al.
Bioorganic & medicinal chemistry, 17(16), 6008-6014 (2009-07-18)
Reactions of pulse radiolytically generated hydroxyl (()OH) radicals and one-electron specific oxidants, Br(2)(-) radicals with bergenin, a polyphenolic tannin derivative, were studied and the transients detected by absorption spectrometry. The transient absorption spectrum produced during the reaction of ()OH radicals
Yusei Kashima et al.
Journal of oleo science, 62(6), 391-401 (2013-06-04)
Here we evaluated the inhibitory effects of bergenin analogues (2-10), prepared from naturally occurring bergenin, (1) on β-secretase (BACE1) activity. All the bergenin analogues that were analyzed inhibited BACE1 in a dose-dependent manner. 11-O-protocatechuoylbergenin (5) was the most potent inhibitor
Xuan Qin et al.
Arzneimittel-Forschung, 60(4), 198-204 (2010-05-22)
The purpose of this study was to explore the absorption characteristics of bergenin (CAS 477-90-7) and to improve its bioavailability by modulation of the gastrointestinal (GI) absorption using two enhancers (borneol and Poloxamer 188, resp. F68) based on in situ
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