蒸汽压
0.8 mmHg ( 20 °C)
方案
≥98.0% (T)
沸点
145-156 °C (lit.)
mp
42-44 °C (lit.)
42-44 °C
SMILES字符串
[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].C1CNCCN1
InChI
1S/C4H10N2.6H2O/c1-2-6-4-3-5-1;;;;;;/h5-6H,1-4H2;6*1H2
InChI key
AVRVZRUEXIEGMP-UHFFFAOYSA-N
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Mitsunori Kono et al.
Bioorganic & medicinal chemistry, 21(1), 28-41 (2012-12-12)
A series of piperazine ureas was designed, synthesized, and evaluated for their potential as novel orally available fatty acid amide hydrolase (FAAH) inhibitors that are therapeutically effective against pain. We carried out an optimization study of the lead compound 3
Yuji Nakamura et al.
Bioorganic & medicinal chemistry letters, 22(14), 4561-4566 (2012-06-26)
Introduction of the 2,2-dimethyl-4-phenylpiperazin-5-one scaffold into the P(3)-P(1) portion of the (2S,4S,5S)-5-amino-6-dialkylamino-4-hydroxy-2-isopropylhexanamide backbone dramatically increased the renin inhibitory activity without using the interaction to the S(3)(sp) pocket. Compound 31 exhibited >10,000-fold selectivity over other human proteases, and 18.5% oral bioavailability
William Conway et al.
The journal of physical chemistry. A, 117(5), 806-813 (2013-01-05)
Piperazine (PZ) is widely recognized as a promising solvent for postcombustion capture (PCC) of carbon dioxide (CO(2)). In view of the highly conflicting data describing the kinetic reactions of CO(2)(aq) in piperazine solutions, the present study focuses on the identification
Leila Hassanzadeh et al.
Nuclear medicine and biology, 40(2), 227-232 (2012-11-13)
It has been recognized that serotonin plays a main role in various pathological conditions such as anxiety, depression, aggressiveness, schizophrenia, suicidal behavior, panic and autism. 1-(2-Methoxyphenyl) piperazine pharmacophore, a fragment of the true 5-HT(1A) antagonist WAY100635, is found in numerous
P Krishnan et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 102, 379-385 (2012-12-12)
Monohydrate piperazine hydrogen phosphate (MPHP), a semi organic nonlinear optical material has been synthesized and single crystals were grown from aqueous solution by slow evaporation technique. Single crystal X-ray diffraction study on grown crystal reveals that they belong to monoclinic
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