84792
东莨菪内酯
purum, ≥98.0% (HPLC)
别名:
6-甲氧基伞形酮, 7-羟基-6-甲氧基-2H-1-苯并吡喃-2-酮, 7-羟基-6-甲氧基香豆素, 七叶亭-6-甲醚, 东莨菪亭, 东莨菪内酯, 柯阿托酸, 莨菪亭, 钩吻酸
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关于此项目
经验公式（希尔记法）:
C10H8O4
化学文摘社编号:
分子量:
192.17
EC Number:
202-171-9
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
156296
MDL number:
Biochem/physiol Actions
东莨菪素通过促进 LPL 基因的转录，显著增强脂肪细胞中脂蛋白脂肪酶的活性。它还部分逆转 TNF-α 对 LPL 的抑制作用。
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
法规信息
新产品
此项目有
Jeong-Yeh Yang et al.
International journal of molecular medicine, 20(4), 527-531 (2007-09-06)
Hypertriglyceridemia is an independent risk factor of cardiovascular diseases. It is caused by the imbalance between hepatic triglyceride production and peripheral removal. Lipoprotein lipase (LPL) plays a central role in the removal of plasma triglyceride. During the screening of possible
Soyoung Kim et al.
Journal of natural products, 69(12), 1769-1775 (2006-12-28)
Two new cyclopenta[b]benzofurans, aglaroxin A 1-O-acetate (2) and 3'-methoxyaglaroxin A 1-O-acetate (3), a new benzo[b]oxepine, 19,20-dehydroedulisone A (4), and five new cyclopenta[bc]benzopyrans, edulirin A (5), edulirin A 10-O-acetate (6), 19,20-dehydroedulirin A (7), isoedulirin A (8), and edulirin B (9), were
Gui-Ping Zhang et al.
Journal of natural products, 72(7), 1265-1268 (2009-07-04)
Six new prenylated isoflavanones named sophoronols A-F (1-6), together with eight phenolic constituents, were isolated from the roots of Sophora mollis. Their structures and stereochemistry were established by 1D and 2D NMR techniques, especially HMBC and NOESY as well as
Jih-Jung Chen et al.
Journal of natural products, 71(2), 212-217 (2008-01-24)
Eight new compounds, including four new neolignans, (7' S,8' S)-bilagrewin ( 1), (7' S,8' S)-5-demethoxybilagrewin ( 2), (7' S,8' S)-5- O-demethyl-4'- O-methylbilagrewin ( 3), and (7' S,8' S)-nocomtal ( 4), a new coumarinolignan, (7' S,8' S)-4'- O-methylcleomiscosin D ( 5)
Anna Maria Ferrari et al.
European journal of medicinal chemistry, 42(7), 1028-1031 (2007-02-24)
Quantum-chemical descriptors related to proton dissociation constants of a set of coumarins hydroxylated in various positions have been computed and related to the experimental pK(a) values. An excellent correlation was found between the computed deprotonation energies of hydroxycoumarins in water
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