85549
Span® 85
别名:
Sorbitan trioleate, Span® 85
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经验公式（希尔记法）:
C60H108O8
化学文摘社编号:
分子量:
957.49
UNSPSC Code:
12161900
PubChem Substance ID:
EC Number:
247-569-3
MDL number:
InChI key
ZBNRGEMZNWHCGA-WECPCUOASA-N
InChI
1S/C60H108O8/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56(62)65-52-54(61)59-60(68-58(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)55(53-66-59)67-57(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h25-30,54-55,59-61H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27+/t54-,55+,59-,60-/m1/s1
SMILES string
CCCCCCCC\C=C/CCCCCCCC(=O)O[C@H](CO)[C@H]1OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC
description
non-ionic
refractive index
n20/D 1.476 (lit.)
viscosity
200-300 mPa.s(20 °C)
HLB value
1.8±1.1
density
0.94 g/mL at 20 °C, 0.956 g/mL at 25 °C (lit.)
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Legal Information
Span is a registered trademark of Croda International PLC
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
437.0 °F
flash_point_c
225 °C
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
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Gülay Büyükköroğlu et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 109, 174-183 (2016-10-30)
Cervical cancer is one of the most life threatening types of cancer among women and is generally resistant to chemotherapy. The objective of this study was to prepare a vaginal suppository containing a chemotherapeutic agent and a genetic material that
Ming-Hsi Huang et al.
PloS one, 5(8), e12279-e12279 (2010-09-03)
Antigen sparing and cross-protective immunity are regarded as crucial in pandemic influenza vaccine development. Both targets can be achieved by adjuvantation strategy to elicit a robust and broadened immune response. We assessed the immunogenicity of an inactivated H5N1 whole-virion vaccine
Determination of sorbitan trioleate in metered-dose inhalers by supercritical-fluid chromatography.
M Di Maso et al.
Journal of pharmaceutical and biomedical analysis, 8(3), 303-305 (1990-01-01)
Effects of different nonionic surfactants on in vitro fermentation characteristics of cereal straws.
Z H Cong et al.
Journal of animal science, 87(3), 1085-1096 (2008-12-23)
The effects of 3 nonionic surfactants (NIS), including alkyl polyglucoside (APG), sorbitan trioleate (Span85), and polyoxyethylene sorbitan monostearate (Tween80), on in vitro fermentation characteristics of maize stover, rice straw, and wheat straw were examined using an in vitro gas production
H Todo et al.
International journal of pharmaceutics, 220(1-2), 101-110 (2001-05-30)
The lungs are useful for administration of macromolecules, which are poorly absorbed from the intestine. In the present study, we prepared several dry powder formulations of insulin using a spray drying technique to examine the effect of additives on insulin
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