85680
硬脂酸
puriss., ≥98.5% (GC)
别名:
1-十八碳烷酸, C18:0, NSC 25956, NSC 261168, 十八烷酸, 硬脂酸
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线性分子式:
CH3(CH2)16COOH
化学文摘社编号:
分子量:
284.48
EC Number:
200-313-4
UNSPSC Code:
12352211
PubChem Substance ID:
Beilstein/REAXYS Number:
608585
MDL number:
InChI key
QIQXTHQIDYTFRH-UHFFFAOYSA-N
InChI
1S/C18H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h2-17H2,1H3,(H,19,20)
SMILES string
CCCCCCCCCCCCCCCCCC(O)=O
vapor pressure
1 mmHg ( 173.7 °C)
grade
puriss.
assay
≥98.5% (GC)
form
flakes (fine), powder or crystals (fine)
ign. residue
≤0.05%
bp
361 °C (lit.)
mp
67-72 °C (lit.), 69-71 °C
functional group
carboxylic acid
shipped in
ambient
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存储类别
11 - Combustible Solids
wgk
nwg
flash_point_f
392.0 °F - Cleveland open cup
flash_point_c
200 °C - Cleveland open cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
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Palle J Pedersen et al.
Journal of medicinal chemistry, 53(9), 3782-3792 (2010-04-22)
The design of retinoid phospholipid prodrugs is described based on molecular dynamics simulations and cytotoxicity studies of synthetic retinoid esters. The prodrugs are degradable by secretory phospholipase A(2) IIA and have potential in liposomal drug delivery targeting tumors. We have
Piret Arukuusk et al.
Biochimica et biophysica acta, 1828(5), 1365-1373 (2013-01-30)
Harnessing of a branched structure is a novel approach in the design of cell-penetrating peptides and it has provided highly efficient transfection reagents for intracellular delivery of nucleic acids. The new stearylated TP10 analogs, NickFects, condense plasmid DNA, splice correcting
S M Grundy
The American journal of clinical nutrition, 60(6 Suppl), 986S-990S (1994-12-01)
Stearic acid is a long-chain saturated fatty acid. However, in contrast with other saturated fatty acids, stearic acid apparently does not raise serum cholesterol concentrations. Studies carried out three decades ago provided strong suggestive evidence that this was the case.
A M Turpeinen et al.
Arteriosclerosis, thrombosis, and vascular biology, 18(2), 316-322 (1998-03-04)
The effects of stearic acid (C18:0) and trans-fatty acids (trans-FAs) on measures of platelet function and prostacyclin (PGI2) production are poorly understood in humans. In this controlled dietary study, platelet function and endothelial PGI2 production were studied in healthy humans
Ulla Hoppu et al.
Journal of pediatric gastroenterology and nutrition, 41(3), 335-338 (2005-09-01)
Breast milk fatty acids may have immunomodulatory properties related to the development of atopic disease. The aim of this study was to assess the impact of the breast milk fatty acid composition on the development of atopic dermatitis (AD) in
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