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Merck
CN

86150

环丁砜

purum, ≥98.0% (GC)

别名:

四亚甲基砜, 四氢噻吩-1,1-二氧化物

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关于此项目

经验公式(希尔记法):
C4H8O2S
化学文摘社编号:
分子量:
120.17
EC Number:
204-783-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
107765
MDL number:
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vapor density

4.2 (vs air)

vapor pressure

0.01 mmHg ( 20 °C)

grade

purum

assay

≥98.0% (GC)

impurities

≤2% water

refractive index

n20/D 1.484 (lit.), n20/D 1.485

bp

104 °C/0.2 mmHg (lit.), 285 °C (lit.)

mp

20-26 °C (lit.)

density

1.261 g/mL at 25 °C (lit.)

SMILES string

O=S1(=O)CCCC1

InChI

1S/C4H8O2S/c5-7(6)3-1-2-4-7/h1-4H2

InChI key

HXJUTPCZVOIRIF-UHFFFAOYSA-N



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pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

350.6 °F - closed cup

flash_point_c

177 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Kevin Aart Douglass et al.
Journal of the American Society for Mass Spectrometry, 23(3), 489-497 (2012-01-06)
The supercharging effect of sulfolane on cytochrome c (cyt c) during electrospray ionization mass spectrometry (ESI-MS) in the absence of conformational effects was investigated. The addition of sulfolane on the order of 1 mM or greater to denaturing solutions of cyt
François Versace et al.
Analytical and bioanalytical chemistry, 404(6-7), 1831-1838 (2012-08-25)
The role of busulfan (Bu) metabolites in the adverse events seen during hematopoietic stem cell transplantation and in drug interactions is not explored. Lack of availability of established analytical methods limits our understanding in this area. The present work describes
R B Burns et al.
Journal of pharmaceutical and biomedical analysis, 13(9), 1073-1078 (1995-08-01)
A gas-chromatographic assay method was developed and validated for determination of busulfan in human plasma for test dose therapeutic drug monitoring. Busulfan and the internal standard (1,6-bis-(methanesulfonyloxy)hexane) were extracted from plasma samples and derivatized with 2,3,5,6-tetrafluorothiophenol prior to gas chromatographic