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Merck
CN

86330

牛磺酸

≥99.0% (T)

别名:

2-氨基乙磺酸

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线性分子式:
NH2CH2CH2SO3H
化学文摘社编号:
分子量:
125.15
EC Number:
203-483-8
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
1751215
MDL number:
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InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

InChI key

XOAAWQZATWQOTB-UHFFFAOYSA-N

SMILES string

NCCS(O)(=O)=O

assay

≥99.0% (T)

ign. residue

≤0.1% (as SO4)

loss

≤0.2% loss on drying, 110 °C

mp

>300 °C (lit.), 328-329 °C (dec.)

solubility

H2O: 0.1 g/mL, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤500 mg/kg

cation traces

As: ≤0.1 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

Gene Information

rat ... Ppm1a(24666)

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Biochem/physiol Actions

甘氨酸受体的非选择性内源激动剂。
甘氨酸受体的非选择性内源激动剂。在某些细胞中调节细胞凋亡的条件必需磺化氨基酸;在许多新陈代谢活动中起作用;是蛋氨酸和半胱氨酸的代谢产物。

存储类别

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M Axelson et al.
Hepatology (Baltimore, Md.), 31(6), 1305-1312 (2000-05-29)
The biosynthesis of bile acids by primary cultures of normal human hepatocytes has been investigated. A general and sensitive method for the isolation and analysis of sterols and bile acids was used, based on anion exchange chromatography and gas chromatography-mass
Tsutomu Suzuki et al.
Wiley interdisciplinary reviews. RNA, 2(3), 376-386 (2011-10-01)
Mitochondrial DNA mutations that cause mitochondrial dysfunction are responsible for a wide spectrum of human diseases, referred to as mitochondrial diseases. Pathogenic point mutations are found frequently in genes encoding mitochondrial (mt) tRNAs, indicating that impaired functioning of mutant mt
Marlene Wewalka et al.
The Journal of clinical endocrinology and metabolism, 99(4), 1442-1451 (2014-01-18)
Bile acids (BAs) are newly recognized signaling molecules in glucose and energy homeostasis. Differences in BA profiles with type 2 diabetes mellitus (T2D) remain incompletely understood. The objective of the study was to assess serum BA composition in impaired glucose-tolerant
Deniz Tasdemir et al.
Bioorganic & medicinal chemistry, 15(21), 6834-6845 (2007-09-04)
The type II fatty acid pathway (FAS-II) is a validated target for antimicrobial drug discovery. An activity-guided isolation procedure based on Plasmodium falciparum enoyl-ACP reductase (PfFabI) enzyme inhibition assay on the n-hexane-, the CHCl(3-) and the aq MeOH extracts of
Zi-Bing Jin et al.
PloS one, 6(2), e17084-e17084 (2011-02-25)
Retinitis pigmentosa (RP) is the most common inherited human eye disease resulting in night blindness and visual defects. It is well known that the disease is caused by rod photoreceptor degeneration; however, it remains incurable, due to the unavailability of

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