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Merck
CN

86900

四丁基氟化铵 溶液

purum, ~1 M in THF

别名:

TBAF 溶液

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关于此项目

线性分子式:
[CH3(CH2)3]4NF
化学文摘社编号:
分子量:
261.46
PubChem Substance ID:
UNSPSC Code:
12352116
Beilstein/REAXYS Number:
3762762
MDL number:
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SMILES string

[F-].CCCC[N+](CCCC)(CCCC)CCCC

InChI

1S/C16H36N.FH/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;/h5-16H2,1-4H3;1H/q+1;/p-1

InChI key

FPGGTKZVZWFYPV-UHFFFAOYSA-M

grade

purum

concentration

~1 M in THF

impurities

4-5% water

storage temp.

2-8°C

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Application

用于制备以下试剂的反应物:
  • 三重单胺再摄取抑制剂,用作新一代抗抑郁药物
  • 在中性pH有机-水混合缓冲溶液中,水解烷基硅醚的醇
  • 磷酸盐修饰键的寡核苷酸
  • 通过手性双吡啶二醇配体和三氯化铬催化Nozaki-Hiyama烯丙基化反应的芳基烷基醇
  • 通过Suzuki偶联反应结合的二烯酸酯
  • 具有抗肿瘤作用的大环邻氨基苯扎胺Hsp90抑制剂
  • 磷酰肌醇3激酶(PI3K)/哺乳动物雷帕霉素(mTOR)双抑制剂的靶点
  • 抗糖尿病聚乙炔糖甙

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system, Respiratory system

supp_hazards

存储类别

3 - Flammable liquids

wgk

WGK 3

flash_point_f

1.4 °F - closed cup

flash_point_c

-17 °C - closed cup

法规信息

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分析证书(COA)

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Fabio Galeotti et al.
Journal of chromatography. A, 1284, 141-147 (2013-03-05)
In this study, by using tetrabutylammonium bisulfate as ion-pairing reagent, we were able to separate all the main heparin/heparan sulfate disaccharides generated by the action of heparinases along with the main Hep tetrasaccharide possessing a 3-O-sulfate group on the sulfoglucosamine
Erbo Shi et al.
Organic letters, 14(13), 3384-3387 (2012-06-27)
A metal-free C-H oxidation for the construction of allylic esters has been developed. The use of a commercially available and inexpensive catalyst and oxidant, and readily available starting materials, coupled with the operational simplicity of the reaction, renders the methodology
Oliver Bixner et al.
The Journal of chemical physics, 136(20), 204503-204503 (2012-06-07)
The interaction of exciton and charge transfer (CT) states plays a central role in photo-induced CT processes in chemistry, biology, and physics. In this work, we use a combination of two-dimensional electronic spectroscopy (2D-ES), pump-probe measurements, and quantum chemistry to
Mei Shen et al.
Journal of the American Chemical Society, 134(24), 9856-9859 (2012-06-05)
Here we report on the unprecedentedly high resolution imaging of ion transport through single nanopores by scanning electrochemical microscopy (SECM). The quantitative SECM image of single nanopores allows for the determination of their structural properties, including their density, shape, and
Ying-Chieh Wong et al.
Organic letters, 14(23), 6024-6027 (2012-11-30)
The radical cascade protocol of the α-cyano α-TMS/aryl-capped alkynyl aryl ketones promoted by tert-butyl hydroperoxide under catalysis with tetrabutylammonium iodide in refluxing benzene has been developed, leading to the construction of a variety of highly functionalized [6,6,5] tricyclic frameworks in

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