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Merck
CN

89180

L-苏氨酸

≥99.0% (NT)

别名:

(2S,3R)-2-氨基-3-羟基丁酸

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线性分子式:
CH3CH(OH)CH(NH2)CO2H
化学文摘社编号:
分子量:
119.12
EC Number:
200-774-1
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
1721646
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InChI

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1

InChI key

AYFVYJQAPQTCCC-GBXIJSLDSA-N

SMILES string

C[C@@H](O)[C@H](N)C(O)=O

assay

≥99.0% (NT)

optical activity

[α]20/D −28.5±0.5°, c = 5% in H2O

impurities

≤0.5% foreign amino acids

ign. residue

≤0.1% (as SO4)

loss

≤0.5% loss on drying, 110 °C

mp

256 °C (dec.) (lit.)

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤50 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, NH4+: ≤500 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

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wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

存储类别

11 - Combustible Solids

法规信息

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Jung-Ah Kang et al.
Journal of immunology (Baltimore, Md. : 1950), 190(9), 4508-4515 (2013-03-27)
Strong NF-κB activation requires ligation of both the CD28 coreceptor and TCR. Phosphoinositide-dependent kinase 1 (PDK1) acts as a scaffold by binding both protein kinase Cθ (PKCθ) and CARMA1, and is therefore essential for signaling to NF-κB. In this article
Lifu Wang et al.
Nature communications, 4, 1559-1559 (2013-03-07)
The AMP-activated protein kinase (AMPK) regulates metabolism in normal and pathological conditions and responds to nutrients, hormones, anti-diabetic drugs and physical exercise. AMPK is activated by the kinase LKB1 and inactivated by phosphatases whose identities remain uncertain. Here we show
Eun Jung Jang et al.
Journal of immunology (Baltimore, Md. : 1950), 190(11), 5764-5770 (2013-04-26)
A T-box-containing protein expressed in T cells (T-bet) is a key transcription factor involved in the regulation of Th cell differentiation. Although T-bet-deficient CD4(+) T cells fail to produce IFN-γ and typically differentiate into Th2 cells in vitro, ectopic overexpression
Yan Liu et al.
FEBS letters, 587(7), 847-853 (2013-02-26)
CREB binding protein (CBP) is an acetyltransferase that plays an important role in many biological processes. Here, we show that Akt phosphorylates CBP at threonine 1871 and suppresses its acetyltransferase activity by impeding the binding of CBP to histone H3
Francesca Siepi et al.
Biochimica et biophysica acta, 1833(6), 1443-1453 (2013-03-15)
HIPK2 (homeodomain-interacting protein kinase-2) binds to and phosphorylates, at Ser and Thr residues, a large number of targets involved in cell division and cell fate decision in response to different physiological or stress stimuli. Inactivation of HIPK2 has been observed

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