方案
≥95%
表单
powder
储存温度
2-8°C
应用
Fluorinated piperidines are of interest in drugs, agrochemicals and materials science. A straightforward process developed by Glorius and coworkers allows the preparation of these motifs in a highly diastereoselective manner. The all-cis-3,5-difluoropiperidine can be directly employed in synthetic applications after TFA-deprotection.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
法规信息
新产品
此项目有
Zackaria Nairoukh et al.
Nature chemistry, 11(3), 264-270 (2019-01-22)
Piperidines and fluorine substituents are both independently indispensable components in pharmaceuticals, agrochemicals and materials. Logically, the incorporation of fluorine atoms into piperidine scaffolds is therefore an area of tremendous potential. However, synthetic approaches towards the formation of these architectures are
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