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Merck
CN

905151

Sigma-Aldrich

(±)-cis-4-fluorocyclohexylboronic acid pinacol ester

≥95% (sum of diastereomers)

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关于此项目

经验公式(希尔记法):
C12H22BFO2
化学文摘社编号:
分子量:
228.11
UNSPSC代码:
12352101
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描述

Diastereomer Ratio: > 8:1

方案

≥95% (sum of diastereomers)

表单

liquid

储存温度

2-8°C

应用

The incorporation of fluorine in agrochemical and pharmaceutical compounds is of high interest due to the ability to fine-tune the polarity, pKA-value, conformation and metabolic stability. Derived from a cis-selective hydrogenation developed by Glorius and coworkers, this boronic ester can be used in various organometallic transformations.

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

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Mario P Wiesenfeldt et al.
Science (New York, N.Y.), 357(6354), 908-912 (2017-08-12)
All-cis-multifluorinated cycloalkanes exhibit intriguing electronic properties. In particular, they display extremely high dipole moments perpendicular to the aliphatic ring, making them highly desired motifs in material science. Very few such motifs have been prepared, as their syntheses require multistep sequences

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