90532
N-Desisopropylpropranolol
analytical standard
别名:
(±)-1-Amino-3-(1-naphthyloxy)-2-propanol, (±)-Norpropranolol, N-Deisopropylpropranolol
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关于此项目
经验公式（希尔记法）:
C13H15NO2
化学文摘社编号:
分子量:
217.26
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
方案
≥97.5% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
杂质
≤1.0% water (calc. from elemental analysis)
应用
pharmaceutical
包装形式
neat
储存温度
2-8°C
SMILES字符串
NCC(O)COC1=CC=CC2=CC=CC=C21
InChI
1S/C13H15NO2/c14-8-11(15)9-16-13-7-3-5-10-4-1-2-6-12(10)13/h1-7,11,15H,8-9,14H2
InChI key
ZFMCITCRZXLMDJ-UHFFFAOYSA-N
一般描述
N-Desisopropylpropranolol is one of the active metabolites of propranolol, a widely prescribed β-adrenergic blocking drug for treating arrhythmias, thyrotoxicosis, angina pectoris, and hypertension.
应用
N-Desisopropylpropranolol may be used as an analytical reference standard for the determination of the analyte in various biological samples by chromatography techniques.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Rapid and simultaneous extraction of propranolol, its neutral and basic metabolites from plasma and assay by high-performance liquid chromatography
Harrison PM, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 343(1), 349-358 (1985)
An improved HPLC-MS/MS method for simultaneous quantification of propranolol and its two phase I metabolites in plasma of infants with hemangioma and its application to a comparative study of plasma concentrations
He H, et al.
Royal Society of Chemistry Advances, 8(65), 37286-37294 (2018)
Versatile isocratic high-performance liquid chromatographic assay for propranolol and its basic, neutral and acidic metabolites in biological fluids
Kwong EC and Shen DD
Journal of Chromatography. B, Biomedical Sciences and Applications, 414(65), 365-379 (1987)
Development and validation of a capillary zone electrophoresis method for the determination of propranolol and N-desisopropylpropranolol in human urine
Nevado JJB, et al.
Analytica Chimica Acta, 559(1), 9-14 (2006)
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