90985
香叶木素
analytical standard
别名:
3′,5,7-三羟基-4′-甲氧基黄酮, 4′-甲基木犀草素, 5,7-二羟基-2-（3-羟基-4-甲氧基苯基）色烯-4-酮, 木犀草素 4′-甲醚
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关于此项目
经验公式（希尔记法）:
C16H12O6
化学文摘社编号:
分子量:
300.26
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
208-291-8
Beilstein/REAXYS Number:
294492
MDL number:
InChI key
MBNGWHIJMBWFHU-UHFFFAOYSA-N
InChI
1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3
SMILES string
COc1ccc(cc1O)C2=CC(=O)c3c(O)cc(O)cc3O2
grade
analytical standard
assay
≥95.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤5.0% water
application(s)
food and beverages
format
neat
storage temp.
2-8°C
Quality Level
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
柑橘柠檬中的类黄酮。抗氧化剂。通过抑制CYP1A1酶抑制致癌物活化。
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Miguel Angel Campanero et al.
Journal of pharmaceutical and biomedical analysis, 51(4), 875-881 (2009-10-06)
Diosmetin (3',5,7-trihydroxy-4'-methoxyflavone) is the aglycone of the flavonoid glycoside diosmin (3',5,7-trihydroxy-4'-methoxyflavone-7-ramnoglucoside). Diosmin is hydrolyzed by enzymes of intestinal micro flora before absorption of its aglycone diosmetin. A specific, sensitive, precise, accurate and robust HPLC assay for the simultaneous determination of
Luigi Quintieri et al.
Drug metabolism and pharmacokinetics, 25(5), 466-476 (2010-09-30)
The aim of this study was to examine in vitro, by means of kinetic analysis and molecular docking simulations, the effects of the flavone diosmetin and its flavanone analog hesperetin on CYP (cytochrome P450) 2C9-mediated drug metabolism. To this purpose
Ya-Ling Hsu et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 23(6), 949-960 (2008-02-14)
The survival of osteoblasts is one of the determinants of the development of osteoporosis. This study is the first to investigate the osteoblastic differentiation induced by diosmetin, a flavonoid derivative, in osteoblastic cell lines MG-63, hFOB, and MC3T3-E1 and bone
Beatriz Abad-García et al.
Rapid communications in mass spectrometry : RCM, 22(12), 1834-1842 (2008-05-13)
Six flavone mono-C-glucosides, four standards (beta-D-glucopyranosyl-(1 --> C-6)- and -(1 --> C-8)- apigenin and luteolin) and two others from lemon juice (beta-D-glucopyranosyl-(1 --> C-6)- and -(1 --> C-8)-diosmetin) have been studied in order to analyze their fragmentation patterns. Initial separation
Helana Naguib Michael et al.
Phytotherapy research : PTR, 27(5), 699-704 (2012-07-05)
The new natural flavonoid compounds - diosmetin 7-O-β-L-arabinofuranosyl (1 → 2) β-D-apiofuranoside (1) and diosmetin 7-O-β-D-apiofuranoside (2) - were isolated from the acetone extract of date fruits epicarp belonging to family Arecaceae (Palmae). Elucidation of their chemical structures was determined by different
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